Disks large homolog 2 Antibodies

AND DLG2 ELISA kits, Disks large homolog 2 Proteins

Many biological assays use antibodies to detect Disks large homolog 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Disks large homolog 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Disks large homolog 2 antibodies...

We validate the specificity of these antibodies to Disks large homolog 2 by testing them on tissues known to express DLG2 positively and negatively. Browse below to find the DLG2 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DLG2 Infographic by Boster Bio

All DLG2 Products

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Specificity

Applications

Price

Anti-PSD-93 DLG2 Antibody

12 Q&As

Human

$399
Cat # A04826
100μl

Anti-PSD93 Monoclonal Antibody

1 Q&As

Human, Mouse, Rat

Flow Cytometry, IP, WB

$370
Cat # M04826
100 μl

Anti-PSD-93 DLG2 Antibody

Human, Mouse, Rat

ICC, WB

$405
Cat # A04826-1
100ul

Anti-PSD93 DLG2 Antibody

Human, Mouse, Rat

Flow Cytometry, IP, WB

$405
Cat # A04826-2
100ul

Anti-PSD-93 DLG2 Antibody

Human

ELISA, IHC, WB

$380
Cat # A04826-3
100ul

DLG2 Overview

Facts about Disks large homolog 2.

DLG2 3D structure. Source: alphafold

Disks large homolog 2 (DLG2)

Required for understanding of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord.

Interacts with the cytoplasmic tail of NMDA receptor subunits in addition to inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses.

Gene Information

Human
Gene Name:	DLG2
Uniprot:	Q15700
Entrez:	1740

Family

Belongs to:

MAGUK family

Alternative Names

Chapsyn-110; discs, large homolog 2 (Drosophila); discs, large homolog 2, chapsyn-110 (Drosophila); discs, large homolog 2, chapsyn-110; disks large homolog 2; DKFZp781D1854; DKFZp781E0954; FLJ37266; MGC131811; Postsynaptic density protein PSD-93; PSD-93; PSD93,110kDa

Molecular Weight

Mass (kDA):
97.552 kDA

Genomic Context


Human

Location:	11q14.1
Sequence:	11; NC_000011.10 (83455009..85628535, complement)

Subcellular Localizations

Cell membrane; Lipid-anchor. Cell junction, synapse, postsynaptic density. Cell junction, synapse. Membrane. Cell projection, axon. Perikaryon. Concentrated in soma and postsynaptic density of a subset of neurons.

Diseases

Neoplasms
Malignant Neoplasms
Tissue Adhesions
Mammary Neoplasms
Ovarian Neoplasm
Mental Disorders
Schizophrenia
Malignant Neoplasm Of Breast
Malignant Neoplasm Of Brain
Kidney Neoplasm
Carcinoma
Chromophobe Renal Cell Carcinoma
Oncocytic Neoplasm

Renal Cell Carcinoma
Chimera Disorder
Stress, Psychological
Benign Neoplasm
Renal Oncocytoma
Genomic Instability
Atrophy

Interacting Proteins

Kcnj2

Pathways

Localization
Cell Adhesion
Transport
Response To Stress
Cell Proliferation
Signal Transmission
Mitosis
Synaptic Transmission
Associative Learning
Neurogenesis
Glucose Homeostasis
Cell Division
Asymmetric Cell Division

Reverse Transcription
Translation
Synaptic Vesicle Exocytosis
Cognition
Exocytosis
Pathogenesis
Epithelial Cell Proliferation

PTMs

Palmitoylation
Phosphorylation

Cleavage
Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DLG2

References

PMID: 8755482 by Kim E., et al. Heteromultimerization and NMDA receptor-clustering activity of Chapsyn-110, a member of the PSD-95 family of proteins.

PMID: 15304517 by Leyland M.L., et al. An alternatively spliced isoform of PSD-93/chapsyn 110 binds to the inwardly rectifying potassium channel, Kir2.1.