DISP3 Antibodies

AND DISP3 ELISA kits, DISP3 Proteins

Many biological assays use antibodies to detect DISP3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DISP3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DISP3 antibodies...

We validate the specificity of these antibodies to DISP3 by testing them on tissues known to express DISP3 positively and negatively. Browse below to find the DISP3 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DISP3 Infographic by Boster Bio

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DISP3 Overview

Facts about Protein dispatched homolog 3.

DISP3 3D structure. Source: alphafold

Protein dispatched homolog 3 (DISP3)

Plays a role in neuronal proliferation and differentiation (PubMed:25281927). Plays a role in the accumulation of cellular cholesterol (By similarity).

Involved in intracellular lipid droplet formation (PubMed:25281927). May contribute to cholesterol homeostasis in neuronal cells (By similarity).

Gene Information

Human
Gene Name:	DISP3
Uniprot:	Q9P2K9
Entrez:	57540

Family

Belongs to:

patched family

Alternative Names

Protein dispatched homolog 3

Molecular Weight

Mass (kDA):
153.048 kDA

Genomic Context


Human

Location:	1p36.22
Sequence:	1; NC_000001.11 (11479155..11537583)

Tissue Specificity

Expressed in brain and testis (PubMed:15645143).

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Predominantly localized to cholesterol-enriched domains within the membrane (PubMed:19179482). Localizes to cytoplasmic punctate vesicular structures (By similarity).

PTMs

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DISP3

References

PMID: 15645143 by Katoh Y., et al. Identification and characterization of DISP3 gene in silico.

PMID: 19179482 by Zikova M., et al. DISP3, a sterol-sensing domain-containing protein that links thyroid hormone action and cholesterol metabolism.