DHRS3 Antibodies

AND DHRS3 ELISA kits, DHRS3 Proteins

Many biological assays use antibodies to detect DHRS3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DHRS3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DHRS3 antibodies...

We validate the specificity of these antibodies to DHRS3 by testing them on tissues known to express DHRS3 positively and negatively. Browse below to find the DHRS3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DHRS3 Infographic by Boster Bio

All DHRS3 Products

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Specificity

Applications

Price

DHRS3 (NM_004753) Human Recombinant Protein

$1062
Cat # PROTO75911
20 µg

DHRS3 (NM_004753) Human Over-expression Lysate

Human

$628
Cat # LS009249
100 µg

DHRS3 Overview

Facts about Short-chain dehydrogenase/reductase 3.

DHRS3 3D structure. Source: alphafold

Short-chain dehydrogenase/reductase 3 (DHRS3)

Catalyzes the reduction of all-trans-retinal to all- trans-retinol in the presence of NADPH. .

Gene Information

Human
Gene Name:	DHRS3
Uniprot:	O75911
Entrez:	9249

Family

Belongs to:

short-chain dehydrogenases/reductases (SDR) family

Alternative Names

DD83.1; dehydrogenase/reductase (SDR family) member 3; EC 1.1.1; EC 1.1.1.300; RDH17; Retinal short-chain dehydrogenase/reductase 1; RETSDR1; retSDR1short chain dehydrogenase/reductase family 16C, member 1; Rsdr1; SDR1; SDR16C1; short-chain dehydrogenase/reductase 1; short-chain dehydrogenase/reductase 3

Molecular Weight

Mass (kDA):
33.548 kDA

Genomic Context


Human

Location:	1p36.21
Sequence:	1; NC_000001.11 (12567910..12618210, complement)

Tissue Specificity

Widely expressed with highest levels found in heart, placenta, lung, liver, kidney, pancreas, thyroid, testis, stomach, trachea and spinal cord. Lower levels found in skeletal muscle, intestine and lymph node. No expression detected in brain. In the retina, expressed in cone but not rod outer segments.

Subcellular Localizations

Membrane; Multi-pass membrane protein.

Diseases

Neoplasms
Malignant Neoplasms
Carcinoma, Papillary
Carcinoma
Papillary Thyroid Carcinoma
Neuroblastoma
Thyroid Neoplasm
Inflammation
Malignant Neoplasm Of Thyroid
Liver Diseases
Neoplasm Metastasis
Kidney Calculi
Vitamin A Deficiency

Metastatic Malignant Neoplasm To The Lymph Node
Neoplasms, Radiation-induced
Melanoma
Tumor Progression
Malignant Neoplasm Of Breast
Carcinogenesis
Nonalcoholic Steatohepatitis

Pathways

Methylation
Gastrulation
Cell Proliferation
Water Homeostasis
Induction Of Apoptosis
Cell Cycle
Dna Methylation

Pathogenesis
Kidney Development

PTMs

Methylation

Demethylation

Oxidation

Research Areas

Vision

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DHRS3

References

PMID: 9705317 by Haeseleer F., et al. Molecular characterization of a novel short-chain dehydrogenase/reductase that reduces all-trans-retinal.

PMID: 11861404 by Cerignoli F., et al. retSDR1, a short-chain retinol dehydrogenase/reductase, is retinoic acid-inducible and frequently deleted in human neuroblastoma cell lines.