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DGUOK Antibodies

AND DGUOK ELISA kits, DGUOK Proteins

Many biological assays use antibodies to detect DGUOK, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DGUOK in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DGUOK antibodies...

We validate the specificity of these antibodies to DGUOK by testing them on tissues known to express DGUOK positively and negatively. Browse below to find the DGUOK antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DGUOK Infographic by Boster Bio

DGUOK protein infographic

All DGUOK Products

Product

Figures

Specificity

Applications

Price

Anti-DGUOK Antibody

Human, Mouse, Rat

WB

$405
Cat # A06092
100ul

Deoxyguanosine kinase (DGUOK) (NM_080916) Human Recombinant Protein

$1249
Cat # PROTQ16854
20 µg

Deoxyguanosine kinase (DGUOK) (NM_080916) Human Over-expression Lysate

Human

$628
Cat # LS001716
100 µg

DGUOK Overview

Facts about Deoxyguanosine kinase, mitochondrial.

DGUOK 3D structure

DGUOK 3D structure. Source: alphafold

Deoxyguanosine kinase, mitochondrial (DGUOK)

Phosphorylates deoxyguanosine and deoxyadenosine in the mitochondrial matrix, with the maximum efficiency for deoxyguanosine. In non-replicating cells, where cytosolic dNTP synthesis is down-regulated, mtDNA synthesis depends solely on DGUOK and TK2.

Phosphorylates certain nucleoside analogs. Widely used as target of antiviral and chemotherapeutic agents.

Gene Information

Human
Gene Name:	DGUOK
Uniprot:	Q16854
Entrez:	1716

Gene Information

Family

Belongs to:

DCK/DGK family

Family

Alternative Names

deoxyguanosine kinase; deoxyguanosine kinase, mitochondrial; DGK; dGKmitochondrial deoxyguanosine kinase; EC 2.7.1.113; MTDPS3

Molecular Weight

Mass (kDA):
32.056 kDA

Molecular Weight

Genomic Context


Human

Location:	2p13.1
Sequence:	2; NC_000002.12 (73926827..73958961)

Tissue Specificity

Ubiquitous. Highest expression in muscle, brain, liver and lymphoid tissues.

Subcellular Localizations

Mitochondrion.

Subcellular Localization

Diseases

Mitochondrial Diseases
Mitochondrial Dna Depletion
Dysmyelopoietic Syndromes
Liver Failure
Muscle Hypotonia
Liver Diseases
Nystagmus
Hypoglycemia
Hepatic Encephalopathy
Liver Failure, Acute
Mitochondrial Myopathies
External Ophthalmoplegia

Ophthalmoplegia
Cholestasis
Acidosis, Lactic
Chronic Progressive External Ophthalmoplegia
Hemochromatosis
Liver Cirrhosis
Neonatal Hemochromatosis

Disease

Pathways

Oxidative Phosphorylation
Transport
Localization
Dna Replication
Pathogenesis
Electron Transport
Electron Transport Chain
Dna Repair
Nucleoside Salvage
Cell Cycle Arrest
Myelination
Mitochondrial Dna Replication

Glucose Homeostasis
Regeneration
Translation
Cell Cycle
Cell Death
Rna Interference

Pathways

PTMs

Phosphorylation

Reduction

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DGUOK

References

PMID: 8692979 by Johansson M., et al. Cloning and expression of human deoxyguanosine kinase cDNA.

PMID: 8706825 by Wang L., et al. Cloning and expression of human mitochondrial deoxyguanosine kinase cDNA.