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- Table of Contents
4 Q&As
Facts about Diacylglycerol kinase zeta.
Positively regulates insulin-induced translocation of SLC2A4 to the cell membrane in adipocytes (By similarity). Activates PIP5K1A action via generation of phosphatidic acid (PubMed:15157668).
Human | |
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Gene Name: | DGKZ |
Uniprot: | Q13574 |
Entrez: | 8525 |
Belongs to: |
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eukaryotic diacylglycerol kinase family |
DAGK5; DAGK6DAG kinase zeta; DGKZ; DGKzeta; DGK-zeta; diacylglycerol kinase zeta; diacylglycerol kinase, zeta 104kDa; diacylglycerol kinase, zeta; Diglyceride kinase zeta; EC 2.7.1.107; hDGKzeta
Mass (kDA):
124.128 kDA
Human | |
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Location: | 11p11.2 |
Sequence: | 11; NC_000011.10 (46332905..46380554) |
Highest levels in brain, and substantial levels in skeletal muscle, heart, and pancreas. Isoform 1 is predominantly expressed in muscle.
Cytoplasm. Nucleus. Cell membrane. Cell projection, lamellipodium.
PMID: 8626588 by Bunting M., et al. Molecular cloning and characterization of a novel human diacylglycerol kinase zeta.
PMID: 9159104 by Ding L., et al. Alternative splicing of the human diacylglycerol kinase zeta gene in muscle.