Diacylglycerol kinase eta Antibodies

AND DGKH ELISA kits, Diacylglycerol kinase eta Proteins

Many biological assays use antibodies to detect Diacylglycerol kinase eta, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Diacylglycerol kinase eta in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Diacylglycerol kinase eta antibodies...

We validate the specificity of these antibodies to Diacylglycerol kinase eta by testing them on tissues known to express DGKH positively and negatively. Browse below to find the DGKH antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DGKH Infographic by Boster Bio

All DGKH Products

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Specificity

Applications

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Anti-Diacylglycerol kinase eta DGKH Antibody

5 Q&As

Human, Mouse

ELISA, IF, IHC-P, ICC

$335
Cat # A07077-1
100ul

DGKH (NM_178009) Human Recombinant Protein

$1249
Cat # PROTQ86XP1
20 µg

DGKH (NM_178009) Human Over-expression Lysate

Human

$960
Cat # LS160851
100 µg

DGKH Overview

Facts about Diacylglycerol kinase eta.

DGKH 3D structure. Source: alphafold

Diacylglycerol kinase eta (DGKH)

Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). Plays a crucial role in promoting cell growth.

Activates the Ras/B-Raf/C-Raf/MEK/ERK signaling pathway induced by EGF. Regulates the recruitment of RAF1 and BRAF from cytoplasm to membranes and their heterodimerization.

Gene Information

Human
Gene Name:	DGKH
Uniprot:	Q86XP1
Entrez:	160851

Family

Belongs to:

eukaryotic diacylglycerol kinase family

Alternative Names

DAG kinase eta; DGKeta; DGK-eta; diacylglycerol kinase eta; diacylglycerol kinase, eta; Diglyceride kinase eta; DKFZp761I1510; EC 2.7.1.107

Molecular Weight

Mass (kDA):
134.866 kDA

Genomic Context


Human

Location:	13q14.11
Sequence:	13; NC_000013.11 (42040036..42256584)

Tissue Specificity

Isoform 2 is ubiquitously expressed. Isoform 1 is expressed only in testis, kidney and colon.

Subcellular Localizations

Cytoplasm. Cell membrane. Translocated from the cytoplasm to endosomes in response to stress stimuli (PubMed:12810723). Isoform 2 is rapidly relocated back to the cytoplasm upon removal of stress stimuli, whereas isoform 1 exhibits sustained endosomal association (PubMed:12810723). Translocates from the cytoplasm to the cell membrane in the presence of active GTP-bound form of HRAS (PubMed:19710016).