DEPTOR Antibodies

AND DEPTOR ELISA kits, DEPTOR Proteins

Many biological assays use antibodies to detect DEPTOR, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DEPTOR in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DEPTOR antibodies...

We validate the specificity of these antibodies to DEPTOR by testing them on tissues known to express DEPTOR positively and negatively. Browse below to find the DEPTOR antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DEPTOR Infographic by Boster Bio

All DEPTOR Products

Product

Figures

Specificity

Applications

Price

Anti-DEPTOR Antibody

Human, Mouse, Rat

ELISA, IHC-P, WB

$449
Cat # A03811
0.1 mg

DEPTOR (NM_022783) Human Over-expression Lysate

Human

$628
Cat # LS064798
100 µg

DEPTOR Overview

Facts about DEP domain-containing mTOR-interacting protein.

DEPTOR 3D structure. Source: alphafold

DEP domain-containing mTOR-interacting protein (DEPTOR)

Negative regulator of the mTORC1 and mTORC2 signaling pathways. Inhibits the kinase activity of both complexes.

Gene Information

Human
Gene Name:	DEPTOR
Uniprot:	Q8TB45
Entrez:	64798

Family

Belongs to:

No superfamily

Alternative Names

DEP domain containing 6; DEP domain containing mTOR interacting protein; DEP domain containing MTOR-interacting protein; DEP domain-containing mTOR-interacting protein; DEP domain-containing protein 6; DEP.6; DEPDC6; DEPDC6FLJ12341; DEPTOR; DKFZp564B1778; FLJ12428; FLJ13854

Molecular Weight

Mass (kDA):
46.294 kDA

Genomic Context


Human

Location:	8q24.12
Sequence:	8; NC_000008.11 (119873655..120050918)

Diseases

Malignant Neoplasms
Multiple Myeloma
Carcinoma
Neoplasms
Cell Transformation, Neoplastic
Neoplasm Metastasis
Malignant Neoplasm Of Liver
Liver Carcinoma
Liver Neoplasms
Disuse Muscle Atrophy
Hepatitis B
Cardiovascular Diseases

Tumor Angiogenesis
Malignant Neoplasm Of Ovary
Mammary Neoplasms
Epithelial Ovarian Cancer
Ovarian Neoplasm
Stress, Psychological

Interacting Proteins

CCDC110
MTOR
Mtor
TRAF1

Pathways

Autophagy
Cell Growth
Senescence
Drug Resistance
Cell Proliferation
Cellular Senescence
Aging
Muscle Atrophy
Cellular Response To Nutrient
Translation
Cell Motility

Cell Cycle
S Phase
Angiogenesis
Response To Nutrient
Pathogenesis
Cell-cell Adhesion

PTMs

Phosphorylation

Ubiquitination

Cleavage

Research Areas

Cancer
Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DEPTOR

References

PMID: 19446321 by Peterson T.R., et al. DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival.

PMID: 30080879 by Zhang H., et al. UBTOR/KIAA1024 regulates neurite outgrowth and neoplasia through mTOR signaling.