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- Table of Contents
Facts about Protein DEK.
Human | |
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Gene Name: | DEK |
Uniprot: | P35659 |
Entrez: | 7913 |
Belongs to: |
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No superfamily |
D6S231EDEK oncogene (DNA binding); DEK oncogene; DEK; protein DEK
Mass (kDA):
42.674 kDA
Human | |
---|---|
Location: | 6p22.3 |
Sequence: | 6; NC_000006.12 (18223860..18264541, complement) |
Ubiquitous. Expressed at relatively high levels.
Nucleus. Enriched in regions where chromatin is decondensed or sparse in the interphase nuclei.
PMID: 1549122 by Von Lindern M., et al. The translocation (6;9), associated with a specific subtype of acute myeloid leukemia, results in the fusion of two genes, dek and can, and the expression of a chimeric, leukemia-specific dek-can mRNA.
PMID: 11118221 by Le Hir H., et al. The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions.