DEGS1 Antibodies

AND DEGS1 ELISA kits, DEGS1 Proteins

Many biological assays use antibodies to detect DEGS1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DEGS1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DEGS1 antibodies...

We validate the specificity of these antibodies to DEGS1 by testing them on tissues known to express DEGS1 positively and negatively. Browse below to find the DEGS1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DEGS1 Infographic by Boster Bio

All DEGS1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

DEGS1 (NM_003676) Human Recombinant Protein

$1062
Cat # PROTO15121
20 µg

Anti-MLD Rabbit Monoclonal Antibody

Human

$370
Cat # M05502
100 μl/vial

DEGS1 (NM_003676) Human Over-expression Lysate

Human

$628
Cat # LS008560
100 µg

DEGS1 Overview

Facts about Sphingolipid delta(4)-desaturase DES1.

DEGS1 3D structure. Source: alphafold

Sphingolipid delta(4)-desaturase DES1 (DEGS1)

Has sphingolipid-delta-4-desaturase activity. Converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine).

Gene Information

Human
Gene Name:	DEGS1
Uniprot:	O15121
Entrez:	8560

Family

Belongs to:

fatty acid desaturase type 1 family

Alternative Names

Cell migration-inducing gene 15 protein; Degenerative spermatocyte homolog 1; degenerative spermatocyte homolog 1, lipid desaturase (Drosophila); degenerative spermatocyte homolog, lipid desaturase (Drosophila); DEGS; Des-1; DES1degenerative spermatocyte homolog, lipid desaturase; EC 1.14; FADS7; membrane fatty acid (lipid) desaturase; Membrane lipid desaturase; MGC5079; migration-inducing gene 15 protein; MLDdihydroceramide desaturase; sphingolipid delta 4 desaturase; sphingolipid delta(4)-desaturase DES1

Molecular Weight

Mass (kDA):
37.866 kDA

Genomic Context


Human

Location:	1q42.11
Sequence:	1; NC_000001.11 (224183240..224193441)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Mitochondrion membrane. Endoplasmic reticulum membrane; Multi-pass membrane protein.

Diseases

Carcinoma
Diabetes Mellitus
Neoplasm Metastasis
Malnutrition
Malignant Neoplasm Of Breast
Hypoxia
Musculoskeletal Diseases
Neoplasm Invasiveness
Carcinogenesis
Malignant Neoplasms
Neoplasms
Innate Immune Response
Asthma

Allergy
Mammary Neoplasms
Anoxia
Esophageal Neoplasms
Abnormal Degeneration
Tissue Adhesions
Atherosclerosis

Pathways

Cell Proliferation
Cell Cycle
Cell Activation
Cell Migration
Innate Immune Response
Lipid Homeostasis
G1 Phase
Response To Hypoxia

Immune Response
Endocytosis

PTMs

Lipoprotein

Myristate

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DEGS1

References

PMID: 9188692 by Cadena D.L., et al. The product of the MLD gene is a member of the membrane fatty acid desaturase family: overexpression of MLD inhibits EGF receptor biosynthesis.

PMID: 11937514 by Ternes P., et al. Identification and characterization of a sphingolipid delta 4- desaturase family.