Defensin-6 Antibodies

AND DEFA6 ELISA kits, Defensin-6 Proteins

Many biological assays use antibodies to detect Defensin-6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Defensin-6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Defensin-6 antibodies...

We validate the specificity of these antibodies to Defensin-6 by testing them on tissues known to express DEFA6 positively and negatively. Browse below to find the DEFA6 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DEFA6 Infographic by Boster Bio

All DEFA6 Products

Product

Figures

Specificity

Applications

Price

Anti-DEF6 DEFA6 Antibody

Human

ELISA, WB

$380
Cat # A09610
100ul

DEFA6 (NM_001926) Human Over-expression Lysate

Human

$628
Cat # LS001671
100 µg

DEFA6 Overview

Facts about Defensin-6.

DEFA6 3D structure. Source: alphafold

Defensin-6 (DEFA6)

Has very low antimicrobial activity against Gram- negative and Gram-positive bacteria. May protect cells from infection with HIV-1.

Gene Information

Human
Gene Name:	DEFA6
Uniprot:	Q01524
Entrez:	1671

Family

Belongs to:

alpha-defensin family

Alternative Names

DEF6HD-6; defensin 6; Defensin, alpha 6; defensin, alpha 6, Paneth cell-specific; defensin-6

Molecular Weight

Mass (kDA):
10.975 kDA

Genomic Context


Human

Location:	8p23.1
Sequence:	8; NC_000008.11 (6924697..6926076, complement)

Tissue Specificity

Paneth cells of the small intestine.

Subcellular Localizations

Secreted.

Diseases

Crohn Disease
Ulcer
Colitis
Ulcerative Colitis
Inflammation
Inflammatory Bowel Diseases
Intestinal Diseases
Malignant Neoplasms
Autoimmunity
Adenoma
Neoplasm Metastasis
Colonic Neoplasms

Malignant Tumor Of Colon
Colonic Diseases
Neoplasms
Pseudomembranous Colitis
Asthma
Lymphoma

Interacting Proteins

UBQLN1
UBQLN2

Pathways

Cell Activation
Cellular Localization
Cell Differentiation
Stem Cell Maintenance
Immune Response
Peptide Secretion
Pathogenesis
Exocytosis

Localization
Secretion
Autophagy

PTMs

Disulfide bond

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DEFA6

References

PMID: 8417977 by Jones D.E., et al. Defensin-6 mRNA in human Paneth cells: implications for antimicrobial peptides in host defense of the human bowel.

PMID: 8626737 by Mallow E.B., et al. Human enteric defensins. Gene structure and developmental expression.