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- Table of Contents
Facts about Probable ATP-dependent RNA helicase DDX60.
Exhibits antiviral activity against hepatitis C virus and vesicular stomatitis virus (VSV). .
Human | |
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Gene Name: | DDX60 |
Uniprot: | Q8IY21 |
Entrez: | 55601 |
Belongs to: |
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helicase family |
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60; DEAD box protein 60
Mass (kDA):
197.853 kDA
Human | |
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Location: | 4q32.3 |
Sequence: | 4; NC_000004.12 (168216293..168325981, complement) |
Brain, lymph node, prostate, stomach, thyroid, tongue, trachea, uterus, skeletal muscle, spleen, kidney, liver and small intestine.
Cytoplasm.
PMID: 21791617 by Miyashita M., et al. DDX60, a DEXD/H box helicase, is a novel antiviral factor promoting RIG-I-like receptor-mediated signaling.
PMID: 21478870 by Schoggins J.W., et al. A diverse range of gene products are effectors of the type I interferon antiviral response.