DDX28 Antibodies

AND DDX28 ELISA kits, DDX28 Proteins

Many biological assays use antibodies to detect DDX28, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DDX28 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DDX28 antibodies...

We validate the specificity of these antibodies to DDX28 by testing them on tissues known to express DDX28 positively and negatively. Browse below to find the DDX28 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DDX28 Infographic by Boster Bio

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DDX28 (NM_018380) Human Over-expression Lysate

Human

$628
Cat # LS055794
100 µg

DDX28 Overview

Facts about Probable ATP-dependent RNA helicase DDX28.

DDX28 3D structure. Source: alphafold

Probable ATP-dependent RNA helicase DDX28 (DDX28)

Plays an essential role in facilitating the correct assembly of the mitochondrial large ribosomal subunit and its helicase activity is vital for this purpose (PubMed:25683708, PubMed:25683715). May be involved in RNA processing or transportation.

Has RNA and Mg(2+)-dependent ATPase activity (PubMed:11350955). .

Gene Information

Human
Gene Name:	DDX28
Uniprot:	Q9NUL7
Entrez:	55794

Family

Belongs to:

DEAD box helicase family

Alternative Names

DEAD (Asp-Glu-Ala-Asp) box polypeptide 28; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 28; EC 3.6.1; EC 3.6.4.13; FLJ11282; M; MDDX28probable ATP-dependent RNA helicase DDX28; Mitochondrial DEAD box protein 28; mitochondrial DEAD-box polypeptide 28

Molecular Weight

Mass (kDA):
59.581 kDA

Genomic Context


Human

Location:	16q22.1
Sequence:	16; NC_000016.10 (68020916..68023232, complement)

Tissue Specificity

Expressed in all tissues tested, including brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, leukocytes, colon, small intestine, ovary and prostate.

Subcellular Localizations

Nucleus. Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid. Mitochondrion matrix. Transported between these two compartments. Nuclear localization depends on active RNA polymerase II transcription. Localizes to mitochondrial RNA granules found in close proximity to the mitochondrial nucleoids.

Diseases

Malignant Neoplasms
Neoplasms
Colorectal Neoplasms
Colorectal Cancer
Carcinogenesis

Pathways

Localization
Transport
Regulation Of Protein Localization
Nuclear Export

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DDX28

References

PMID: 11350955 by Valgardsdottir R., et al. Cloning and characterization of MDDX28, a putative dead-box helicase with mitochondrial and nuclear localization.

PMID: 25683708 by Tu Y.T., et al. The human mitochondrial DEAD-box protein DDX28 resides in RNA granules and functions in mitoribosome assembly.