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- Table of Contents
Facts about ATP-dependent RNA helicase DDX25.
ATP-dependent RNA helicase.
Required for mRNA export and translation regulation during spermatid development (By similarity)..
Human | |
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Gene Name: | DDX25 |
Uniprot: | Q9UHL0 |
Entrez: | 29118 |
Belongs to: |
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DEAD box helicase family |
DEAD (Asp-Glu-Ala-Asp) box polypeptide 25; DEAD box protein 25; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 25; EC 3.6.1; EC 3.6.4.13; Gonadotropin-regulated testicular RNA helicase; GRTHATP-dependent RNA helicase DDX25
Mass (kDA):
54.692 kDA
Human | |
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Location: | 11q24.2 |
Sequence: | 11; NC_000011.10 (125903328..125928843) |
Highly expressed in the Leydig and germ cells of the testis and weakly expressed in the pituitary and hypothalamus.
Cytoplasm. Nucleus. Detected in both cytoplasm and nucleus of testicular cells. Also detected in chromatoid bodies of round spermatids (By similarity).
PMID: 10608860 by Tang P.-Z., et al. A novel gonadotropin-regulated testicular RNA helicase: a new member of the DEAD-box family.
PMID: 20941364 by Schutz P., et al. Comparative structural analysis of human DEAD-box RNA helicases.