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- Table of Contents
Facts about Catenin alpha-3.
Human | |
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Gene Name: | CTNNA3 |
Uniprot: | Q9UI47 |
Entrez: | 29119 |
Belongs to: |
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vinculin/alpha-catenin family |
Alpha T-catenin; alpha-catenin-like protein; alpha-T-catenin; Cadherin-associated protein; catenin (cadherin-associated protein), alpha 3; catenin alpha-3; MGC26194; MGC75041; VR22
Mass (kDA):
99.809 kDA
Human | |
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Location: | 10q21.3 |
Sequence: | 10; NC_000010.11 (65912518..67696217, complement) |
Predominantly expressed in heart and testis. Expressed at lower levels in brain, kidney, liver and skeletal muscle.
Cytoplasm, cytoskeleton. Localizes to intercalated disks of cardiomyocytes and in peritubular myoid cells of testis, and colocalizes with CTNNA1 and CTNNA2.
PMID: 11590244 by Janssens B., et al. AlphaT-catenin: a novel tissue-specific beta-catenin-binding protein mediating strong cell-cell adhesion.
PMID: 12596047 by Janssens B., et al. Assessment of the CTNNA3 gene encoding human alpha T-catenin regarding its involvement in dilated cardiomyopathy.