Dermcidin Antibodies

Dermcidin (DCD)

DCD-1 displays antimicrobial activity thereby limiting skin infection by potential pathogens in the first few hours after bacterial colonization. Highly effective against E.

coli, E.faecalis, S.

Gene Information

Human
Gene Name:	DCD
Uniprot:	P81605
Entrez:	117159

Family

Belongs to:
No superfamily

Alternative Names

AIDDdiffusible survival/evasion peptide; DCD-1; dermcidin; DSEPpreproteolysin; HCAP; MGC71930; PIF; Preproteolysin; proteolysis inducing factor; survival promoting peptide

Molecular Weight

Mass (kDA):
11.284 kDA

Genomic Context

Human
Location:	12q13.2
Sequence:	12; NC_000012.12 (54644589..54648365, complement)

Tissue Specificity

Specifically and constitutively expressed in eccrine sweat gland cells. Secreted into the sweat at a concentration of 1-10 micrograms/ml.

Subcellular Localizations

Secreted.

Diseases

• Abnormal Coordination
• Developmental Coordination Disorder
• Motor Skills Disorders
• Cardiac Death
• Brain Death
• Attention Deficit Hyperactivity Disorder
• Ischemia
• Malnutrition
• Developmental Disabilities
• Delayed Graft Function
• Warm Ischemia
• Cardiac Arrest
• Cold Ischemia

• Reperfusion Injury
• Apraxias
• Neoplasms
• Brain Injuries
• Psychomotor Disorders
• Malignant Neoplasms
• Pain

Interacting Proteins

• APPBP2

Pathways

• Cell Death
• Mitochondrial Depolarization
• Inflammatory Response
• Secretion
• Pathogenesis
• Excretion
• Transport
• Fertilization
• Cognition
• Dna Replication
• Coagulation
• Glycolysis
• Brain Development

• Proteolysis
• Sensitization
• Membrane Depolarization
• Wound Healing
• Insulin Secretion
• Mitosis
• Localization

PTMs

• Nitration
• Oxidation
• Phosphorylation

• Reduction
• Deamination
• Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DCD

Best Uses Of The DCD Marker

What are the benefits of using the DCD Marker? What are the most effective applications? Learn more about Steven Boster. Scientists who seek to find new ways to fight diseases need high-affinity prim antibodies. This article will discuss the benefits of using this marker. It also explains how it works and provides an overview on Boster's past. Its applications go beyond cancer research and clinical trials.

Primary antibodies of high affinity

The boster BioPCD platform produces high-affinity clones that can be used in a variety of applications including Diagnostics & Therapeutics. This proprietary chemistry stops the release of antibodies from B cells, and keeps them on the cell's membranes. Plasma cells and splenocytes are incubated with flurochrome conjugated antigens to generate clones. For downstream screening, the best clones will be isolated.

Flow cytometry has many applications in science. This technique samples particles and cells using antibodies to analyze their interactions. Boster's monoclonal as well as polyclonal high-affinity prima antibodies have received many citations over 25 years. Boster Bio's ELISA Kits will help you find the best antibody to match your application.

Primary antibodies are immunoglobulins formed from the immune system in host animals. They contain a region known as complementarity-determining regions, which is a complex topic. Visit the Wikipedia page for more information. Scientists make polyclonal primary antibodies by immunizing host animals with antigens. They then collect antibodies from the host animals' serum or eggs. Once they are isolated, they undergo further application testing.

Enzyme-linked immunosorbents assays use a combination antibodies to bind target antigens and a detection technique to detect them. Boster Bio is skilled at coating plates with high-affinity antibodies for enzyme-linked immunosorbent (ELISA) assays. This increases the assay's sensitivity. Scientists worldwide trust these products and have the highest confidence in them.

The boster Bio process provides a complete range of deliverables to the customer. The customer will receive an ELISA Data File, a map and purified antibody as well as 100 ng of heavy strand plasmid gene DNA. These samples allow customers to determine which antibodies are most effective and which ones are more difficult to detect. In addition to high-affinity primary antibodies, Boster Bio also offers custom antibody-made recombinant antibodies for research purposes.

The primary-secondary system of antibody provides dual-labeling for specimens. This allows researchers greater flexibility to ask more and obtain better contextual data. The resulting data are more robust than those produced by the monoclonal antibody alone. High-affinity secondary antibodies can produce highly specific results when combined with high-affinity primaries. These antibodies are ideal to be used in high-throughput applications. These antibodies come in different sizes and can be used with different imaging techniques.

History of Steven Boster

If you are curious about Steve Boster's past, you might have wondered how this gifted inventor made it to the top. It all began with a 1993 product he created. He was nicknamed "he Who Converts Science in the Bathroom" and went onto develop hundreds of primary antibodies as well as various products for immunohistochemistry. He was the founder of PicoKine(tm), a proprietary ELISA platform and the largest Chinese antibody catalog company by the late 1990s. This platform is based on trade secrets and delivers high-sensitivity ELISA products to scientists around the globe.

Steve Boster died on June 6, 2022. He was born in Joliet, IL to James and Evelyn Meier. He was a U.S. Army Veteran and belonged at Concordia Hall of Staunton. His wife Linda, his two daughters Crystal Boster (and Natosha) Peck, 6 grandchildren and four brothers, Jack Boster and Sandra Boster, as well as his sister Tammy. Numerous nieces and nephews are also survivors of Steve.