DCAF7 Antibodies

AND DCAF7 ELISA kits, DCAF7 Proteins

Many biological assays use antibodies to detect DCAF7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DCAF7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DCAF7 antibodies...

We validate the specificity of these antibodies to DCAF7 by testing them on tissues known to express DCAF7 positively and negatively. Browse below to find the DCAF7 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DCAF7 Infographic by Boster Bio

All DCAF7 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Human DCAF7 Recombinant Protein

SDS-PAGE, Denatured

$250
Cat # PROTP61962
Starting from 20ug

Anti-DCAF7 Rabbit Monoclonal Antibody

Human, Mouse, Rat

Flow Cytometry, IHC, WB

$370
Cat # M08577
100 μl/vial

WDR68 (DCAF7) (NM_005828) Human Over-expression Lysate

Human

$628
Cat # LS010238
100 µg

DCAF7 Overview

Facts about DDB1- and CUL4-associated factor 7.

DCAF7 3D structure. Source: alphafold

DDB1- and CUL4-associated factor 7 (DCAF7)

Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equal, the palatoquadrate.

The activity necessary for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity.

Gene Information

Human
Gene Name:	DCAF7
Uniprot:	P61962
Entrez:	10238

Family

Belongs to:

WD repeat DCAF7 family

Alternative Names

DDB1 and CUL4 associated factor 7; DDB1- and CUL4-associated factor 7; HAN11AN11; human anthocyanin; seven-WD-repeat protein of the AN11 family-1; SWAN-1; WD repeat domain 68; WD repeat-containing protein 68; WD repeat-containing protein An11 homolog; WDR68; WD-repeat protein

Molecular Weight

Mass (kDA):
38.926 kDA

Genomic Context


Human

Location:	17q23.3
Sequence:	17; NC_000017.11 (63550477..63594266)

Subcellular Localizations

Cytoplasm. Nucleus. Overexpression of DIAHP1 or active RHOA causes translocation from the nucleus to cytoplasm.

Diseases

Cell Transformation, Neoplastic
Skin Neoplasms
Congenital Abnormality
Malignant Neoplasm Of Breast
Campomelic Dysplasia
Craniofacial Abnormalities
Epidermodysplasia Verruciformis
Down Syndrome
Ehlers-danlos Syndrome
Crest Syndrome

Dysplasia
Malignant Neoplasms
Metaplastic Cell Transformation
Congenital Diverticulum Of Pharynx
Mammary Neoplasms

Interacting Proteins

DYRK1A
DYRK1B
HIPK2
MAP3K1

Pathways

Endoderm Formation
Myotube Differentiation
Gastrulation
Cell Proliferation
Signal Transmission
Nodal Signaling Pathway
Pigmentation

Rna Interference
Oncogenesis

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DCAF7

References

PMID: 9192870 by de Vetten N., et al. The an11 locus controlling flower pigmentation in petunia encodes a novel WD-repeat protein conserved in yeast, plants, and animals.

PMID: 14593110 by Skurat A.V., et al. Phosphorylation of Ser640 in muscle glycogen synthase by DYRK family protein kinases.