DAZL Antibodies

AND DAZL ELISA kits, DAZL Proteins

Many biological assays use antibodies to detect DAZL, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DAZL in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DAZL antibodies...

We validate the specificity of these antibodies to DAZL by testing them on tissues known to express DAZL positively and negatively. Browse below to find the DAZL antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DAZL Infographic by Boster Bio

All DAZL Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-DAZL Monoclonal Antibody

5 Q&As

Human

$370
Cat # M02069
100 μl

Anti-DAZL Picoband® Antibody

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A02069-2
100 μg/vial

Anti-Deleted in azoospermia-like DAZL Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A02069
100ul

DAZL Overview

Facts about Deleted in azoospermia-like.

DAZL 3D structure. Source: alphafold

Deleted in azoospermia-like (DAZL)

RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis.

Acts by binding to the 3'-UTR of mRNA, especially recognizing GUU triplets, and thereby regulating the translation of key transcripts (By similarity). .

Gene Information

Human
Gene Name:	DAZL
Uniprot:	Q92904
Entrez:	1618

Family

Belongs to:

RRM DAZ family

Alternative Names

DAZHSPGY-like-autosomal; DAZL1DAZ-like autosomal; DAZLA; Deleted in azoospermia-like 1; deleted in azoospermia-like; germline specific RNA binding protein; MGC26406; spermatogenesis gene on the Y-like autosomal; SPGYLADAZ homolog

Molecular Weight

Mass (kDA):
33.178 kDA

Genomic Context


Human

Location:	3p24.3
Sequence:	3; NC_000003.12 (16586792..16605423, complement)

Tissue Specificity

Testis specific.

Subcellular Localizations

Cytoplasm. Nucleus. Predominantly cytoplasmic. Nuclear in spermatogonia until near the end of the meiotic prophase and cytoplasmic localization from then onward.

Diseases

Infertility
Azoospermia
Male Infertility
Oligospermia
Sterility
Congenital Absence Of Germinal Epithelium Of Testes
Growth Arrest
Female Infertility
Neoplasms
Premature Menopause
Testicular Neoplasms
Seminoma
Teratoma

Turner Syndrome
Spermatogenesis Arrest
Spermatogenesis Abnormal
Malignant Neoplasms
5,10-methylenetetrahydrofolate Reductase Deficiency
Dysequilibrium Syndrome
Hereditary Diseases

Pathways

Spermatogenesis
Germ Cell Development
Cell Development
Meiosis
Translation
Cell Differentiation
Oogenesis
Localization
Oocyte Maturation
Pachytene
Prophase
Methylation
Cell Proliferation

Cell Cycle
Dna Methylation
Ovulation
Fertilization
Pathogenesis
Stem Cell Differentiation
Menopause

PTMs

Methylation
Cleavage
Demethylation

Phosphorylation
Acetylation
Deacetylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DAZL

References

PMID: 8896558 by Saxena R., et al. The DAZ gene cluster on the human Y chromosome arose from an autosomal gene that was transposed, repeatedly amplified and pruned.

PMID: 8968755 by Shan Z., et al. A SPGY copy homologous to the mouse gene Dazla and the Drosophila gene boule is autosomal and expressed only in the human male gonad.