DAZ3 Antibodies

AND DAZ3 ELISA kits, DAZ3 Proteins

Many biological assays use antibodies to detect DAZ3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DAZ3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DAZ3 antibodies...

We validate the specificity of these antibodies to DAZ3 by testing them on tissues known to express DAZ3 positively and negatively. Browse below to find the DAZ3 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DAZ3 Infographic by Boster Bio

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DAZ3 Overview

Facts about Deleted in azoospermia protein 3.

DAZ3 3D structure. Source: alphafold

Deleted in azoospermia protein 3 (DAZ3)

RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation.

Gene Information

Human
Gene Name:	DAZ3
Uniprot:	Q9NR90
Entrez:	57054

Family

Belongs to:

RRM DAZ family

Alternative Names

deleted in azoospermia 3; deleted in azoospermia protein 3; MGC126441; pDP1679

Molecular Weight

Mass (kDA):
54.989 kDA

Genomic Context


Human

Location:	Yq11.23
Sequence:	Y; NC_000024.10 (24763069..24813492, complement)

Tissue Specificity

Testis specific.

Subcellular Localizations

Cytoplasm. Nucleus. Predominantly cytoplasmic. Nuclear at some stages of spermatozoide development. Localizes both to the nuclei and cytoplasm of spermatozoide differentiation. Nuclear in fetal gonocytes and in spermatogonial nuclei. It then relocates to the cytoplasm during male meiosis.

Diseases

Infertility
Oligospermia
Male Infertility
Azoospermia
Congenital Absence Of Germinal Epithelium Of Testes
Sex Chromosome Disorders Of Sex Development
Spermatogenesis Arrest
Partial Deletion Of Y

Chromosome Inversion
Sex Chromosome Aberrations

Pathways

Spermatogenesis
Gene Conversion

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DAZ3

References

PMID: 10936047 by Saxena R., et al. Four DAZ genes in two clusters found in the AZFc region of the human Y chromosome.

PMID: 10857750 by Tsui S., et al. Identification of two novel proteins that interact with germ-cell- specific RNA-binding proteins DAZ and DAZL1.