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- Table of Contents
Facts about D-amino-acid oxidase.
Regulates the level of the neuromodulator D-serine in the Mind.
Has high activity towards D-DOPA and leads to dopamine synthesis.Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on various D- amino acids with a preference for individuals having small hydrophobic side chains followed by those bearing polar, aromatic, and fundamental groups.
Human | |
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Gene Name: | DAO |
Uniprot: | P14920 |
Entrez: | 1610 |
Belongs to: |
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DAMOX/DASOX family |
DAAO; D-Amino Acid Oxidase; D-amino-acid oxidase; DAMOX; DAMOXOXDA; DAO; EC 1.4.3; EC 1.4.3.3; MGC35381; OXDA
Mass (kDA):
39.474 kDA
Human | |
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Location: | 12q24.11 |
Sequence: | 12; NC_000012.12 (108880030..108901043) |
Peroxisome.
PMID: 2901986 by Momoi K., et al. Molecular cloning and sequence analysis of cDNA encoding human kidney D-amino acid oxidase.
PMID: 1356107 by Fukui K., et al. Molecular cloning and chromosomal localization of a human gene encoding D-amino-acid oxidase.