Fractalkine Antibodies

AND CX3CL1 ELISA kits, Fractalkine Proteins

Many biological assays use antibodies to detect Fractalkine, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Fractalkine in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Fractalkine antibodies...

We validate the specificity of these antibodies to Fractalkine by testing them on tissues known to express CX3CL1 positively and negatively. Browse below to find the CX3CL1 antibody that suites your experiment. We have 9 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CX3CL1 Infographic by Boster Bio

All CX3CL1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Human Fractalkine/CX3CL1 ELISA Kit PicoKine®

4 Citations 6 Q&As

Human

ELISA

$499
Cat # EK0356
96 wells/kit, with removable strips.

Mouse Fractalkine/CX3CL1 ELISA Kit PicoKine®

7 Q&As

Mouse

ELISA

$499
Cat # EK0357
96 wells/kit, with removable strips.

Rat Fractalkine/CX3CL1 ELISA Kit PicoKine®

1 Citations 9 Q&As

Rat

ELISA

$499
Cat # EK0358
96 wells/kit, with removable strips.

Anti-Fractalkine CX3CL1 Antibody Picoband®

3 Citations 3 Q&As

Human

$370
Cat # PA1400
100 μg/vial

Anti-Fractalkine CX3CL1 Antibody Picoband®

1 Citations 17 Q&As

Mouse, Rat

IHC, WB

$370
Cat # PA1401
100 μg/vial

Fractalkine Mouse Recombinant Protein (CX3CL1)

Mouse

$250
Cat # PROTO35188
5ug, 20ug, 1mg

Fractalkine Rat Recombinant Protein (CX3CL1)

Rat

$250
Cat # PROTO55145
5ug, 20ug, 1mg

Anti-Fractalkine CX3CL1 Antibody

Human

ELISA, IHC, WB

$380
Cat # A00882
100ul

Human CX3CL1/Fractalkine Recombinant Protein

SDS-PAGE

$275
Cat # PROTP78423
Starting from 10ug

CX3CL1 Overview

Facts about Fractalkine.

CX3CL1 3D structure. Source: alphafold

Fractalkine (CX3CL1)

Binds to CX3CR1 (PubMed:23125415, PubMed:9931005, PubMed:21829356). Binds to integrins ITGAV:ITGB3 and ITGA4:ITGB1.

Can activate integrins in both a CX3CR1-dependent and CX3CR1-independent method. In the presence of CX3CR1, activates integrins by binding to the classical ligand-binding site (site 1) in integrins.

Gene Information

Human
Gene Name:	CX3CL1
Uniprot:	P78423
Entrez:	6376

Family

Belongs to:

intercrine delta family

Alternative Names

ABCD-3; C3Xkine; chemokine (C-X3-C motif) ligand 1; CX3C membrane-anchored chemokine; CX3CL1; CXC3; CXC3C; FKN; Fractalkine; Neurotactin; neurotactin); NTNsmall inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine; NTTSmall-inducible cytokine D1; SCYD1C-X3-C motif chemokine 1; small inducible cytokine subfamily D (Cys-X3-Cys), member-1

Molecular Weight

Mass (kDA):
42.203 kDA

Genomic Context


Human

Location:	16q21
Sequence:	16; NC_000016.10 (57372490..57385044)

Tissue Specificity

Expressed in the seminal plasma, endometrial fluid and follicular fluid (at protein level). Small intestine, colon, testis, prostate, heart, brain, lung, skeletal muscle, kidney and pancreas. Most abundant in the brain and heart.

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein.; [Processed fractalkine]: Secreted.

Diseases

Tissue Adhesions
Inflammation
Neoplasms
Atherosclerosis
Nervousness
Malignant Neoplasms
Arthritis
Rheumatoid Arthritis
Inflammatory Response
Autoimmune Reaction
Pain
Cholangiocarcinoma

Sclerosis
Hiv Infections
Arteriosclerosis
Neoplasm Metastasis
Pertussis
Carcinoma
Multiple Sclerosis

Interacting Proteins

ITGB1
ITGB3

Pathways

Pathogenesis
Chemotaxis
Cell Adhesion
Immune Response
Secretion
Inflammatory Response
Cell Migration
Localization
Angiogenesis
Leukocyte Migration
Cell Proliferation
Cell Death
Cell Activation

Cytokine Production
Neuroprotection
Chemokine Production
Cell-cell Adhesion
Fractalkine Production
Phagocytosis
Monocyte Chemotaxis

PTMs

Phosphorylation
Cleavage
Glycosylation

Reduction
Oxidation
Methylation

Palmitoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CX3CL1

References

PMID: 9177350 by Pan Y., et al. Neurotactin, a membrane-anchored chemokine upregulated in brain inflammation.

PMID: 9024663 by Bazan J.F., et al. A new class of membrane-bound chemokine with a CX3C motif.

9 Publications of Boster Fractalkine Antibodies & ELISA Kits

PubMed ID: PMID:31966515, Identification of genes involved in enterovirus 71 infected SK-N-SH cells
PubMed ID: 10.7150/thno.54235, Vertebral-specific activation of the CX3CL1/ICAM-1 signaling network mediates no...
PubMed ID: 10.1177/2472555216685519, Identification and Validation of Gene Expression Patterns in Cystitis Glandulari...
PubMed ID: 10.1016/j.omto.2021.07.014, Systemic delivery of TNF-armed myxoma virus plus immune checkpoint inhibitor eli...
PubMed ID: 10.1002/ar.22430, Distribution Change of Mast Cells in Human Nasal Polyps
PubMed ID: 10.1002/ar.22430, Distribution Change of Mast Cells in Human Nasal Polyps
PubMed ID: 10.1002/ar.22430, Distribution Change of Mast Cells in Human Nasal Polyps
PubMed ID: -, Yamada,S.,Miyoshi,S.,Nishio,J.,Mizutani,S.,Yamada,Z.,Kusunoki,N.,Sato,H.,Kuboi,Y...
PubMed ID: 28845732, Zhao, B., He, E., Pan, Y., Xu, H., & Song, X. (2017). Kindlin-1 is a key protein...

*More publications can be found for each product on its corresponding product page