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CRMP1 Antibodies
AND CRMP1 ELISA kits, CRMP1 Proteins
Many biological assays use antibodies to detect CRMP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CRMP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CRMP1 antibodies...
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CRMP1 Infographic by Boster Bio
All CRMP1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M05002-1
100 μl/vial
Cat # M05002-1
100 μl/vial
CRMP1 Overview
Facts about Dihydropyrimidinase-related protein 1.
Dihydropyrimidinase-related protein 1 (CRMP1)
Necessary for indicating by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.
May participate in cytokinesis. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CRMP1 |
| Uniprot: | Q14194 |
| Entrez: | 1400 |
Family
| Belongs to: |
|---|
| metallo-dependent hydrolases superfamily |
Alternative Names
collapsin response mediator protein 1DRP1; CRMP-1; dihydropyrimidinase-like 1; dihydropyrimidinase-related protein 1; DPYSL1DRP-1dihydropyrimidinase related protein-1; ULIP3; ULIP-3; Unc-33-like phosphoprotein 3
Molecular Weight
Mass (kDA):
62.184 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 4p16.2 |
| Sequence: | 4; NC_000004.12 (5820764..5893086, complement) |
Tissue Specificity
Brain.
Subcellular Localizations
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cell projection, growth cone. Cytoplasm, cytoskeleton. Perikaryon. Associated with centrosomes and the mitotic spindle during metaphase (PubMed:11562390). Colocalizes with FLNA and tubulin in the central region of DRG neuron growth cone (By similarity). Following SEMA3A stimulation of DRG neurons, colocalizes with F-actin (By similarity).
Diseases
- Neoplasm Invasiveness
- Malignant Neoplasms
- Neoplasms
- Cell Invasion
- Nervousness
- Lung Neoplasms
- Neoplasm Metastasis
- Malignant Neoplasm Of Lung
- Non-small Cell Lung Carcinoma
- Neuroblastoma
- Metastatic Malignant Neoplasm To The Lymph Node
- Carcinoma
- Pituitary Diseases
Interacting Proteins
- AP3M1
- AXIN1
- DPYSL2
- HTT
- VIM
Pathways
- Cell Death
- Mitochondrial Fission
- Neurogenesis
- Axon Guidance
- Cell Adhesion
- Hyperphosphorylation
- Cell Migration
- Programmed Cell Death
- Brain Development
- Mitochondrial Fusion
- System Development
- Nervous System Development
- Spermatogenesis
PTMs
- Phosphorylation
Research Areas
- Neuroscience
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CRMP1
bosterbio.com/bosterbio-gene-info-cards/CRMP1
References
PMID: 8973361 by Hamajima N., et al. A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution.
PMID: 19362386 by Pan S.-H., et al. Long form collapsin response mediator protein-1 (LCRMP-1) expression is associated with clinical outcome and lymph node metastasis in non- small cell lung cancer patients.