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- Table of Contents
Facts about Conserved oligomeric Golgi complex subunit 3.
Involved in ER-Golgi transport.
.Human | |
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Gene Name: | COG3 |
Uniprot: | Q96JB2 |
Entrez: | 83548 |
Belongs to: |
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COG3 family |
COG complex subunit 3; component of oligomeric golgi complex 3p94; SEC34conserved oligomeric Golgi complex subunit 3; tethering factor SEC34; Vesicle-docking protein SEC34 homolog
Mass (kDA):
94.096 kDA
Human | |
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Location: | 13q14.13 |
Sequence: | 13; NC_000013.11 (45464916..45536701) |
Widely expressed with highest levels in pancreas and testis and lowest levels in lung.
Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Associated with the peripheral membrane of cis/medial cisternae.
PMID: 11292827 by Suvorova E.S., et al. Identification of a human ortholog of Sec34p as a component of the cis-Golgi vesicle tethering machinery.
PMID: 11929878 by Loh E., et al. Sec34 is implicated in traffic from the endoplasmic reticulum to the Golgi and exists in a complex with GTC-90 and ldlBp.