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, No Gclids
Calmegin Antibodies
AND CLGN ELISA kits, Calmegin Proteins
Many biological assays use antibodies to detect Calmegin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Calmegin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Calmegin antibodies...
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CLGN Infographic by Boster Bio
All CLGN Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IP, IF, IHC, ICC, WB
$370
Cat # M05261
100 μl/vial
Cat # M05261
100 μl/vial
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M05261-1
100 μl/vial
Cat # M05261-1
100 μl/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A05261-1
100 μg/vial
Cat # A05261-1
100 μg/vial
CLGN Overview
Facts about Calmegin.
Calmegin (CLGN)
Functions during spermatogenesis as a chaperone for a selection of client proteins which are important for sperm adhesion onto the egg zona pellucida and for subsequent penetration of the zona pellucida. Required for normal sperm migration from the uterus into the oviduct.
Required for normal male fertility. Binds calcium ions (By similarity).
Gene Information
| Human | |
|---|---|
| Gene Name: | CLGN |
| Uniprot: | O14967 |
| Entrez: | 1047 |
Family
| Belongs to: |
|---|
| calreticulin family |
Alternative Names
calmegin
Molecular Weight
Mass (kDA):
70.039 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 4q31.1 |
| Sequence: | 4; NC_000004.12 (140388453..140427661, complement) |
Tissue Specificity
Detected in testis (at protein level). Detected in testis.
Subcellular Localizations
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Diseases
- Male Infertility
- Infertility
- Malignant Neoplasms
- Neoplasms
- Adenoma
- Testicular Neoplasms
- Multiple Malignancy
- Seminoma
- Genomic Instability
Pathways
- Fertilization
- Spermatogenesis
- Transport
- Prophase
- Reverse Transcription
- Diplotene
- Cell Differentiation
PTMs
- Acetylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CLGN
bosterbio.com/bosterbio-gene-info-cards/CLGN
References
PMID: 9434179 by Tanaka H., et al. Cloning and characterization of the human Calmegin gene encoding putative testis-specific chaperone.
PMID: 17507649 by van Lith M., et al. A developmentally regulated chaperone complex for the endoplasmic reticulum of male haploid germ cells.