Cdt1 Antibodies

AND Cdt1 ELISA kits, Cdt1 Proteins

Many biological assays use antibodies to detect Cdt1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cdt1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cdt1 antibodies...

We validate the specificity of these antibodies to Cdt1 by testing them on tissues known to express Cdt1 positively and negatively. Browse below to find the Cdt1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Cdt1 Infographic by Boster Bio

All Cdt1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-CDT1 Rabbit Monoclonal Antibody

4 Q&As

Human

IP, IF, IHC, ICC, WB

$370
Cat # M01035
100 μl

Anti-DNA replication factor Cdt1 CDT1 Antibody

Human

IP, IHC, WB

$405
Cat # A01035
100ul

Anti-CDT1/DUP Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, WB

$370
Cat # A01035-1
100 μg/vial

Anti-DUP/CDT1 Antibody Picoband®

Human, Mouse

ELISA, WB

$370
Cat # A01035-2
100 μg/vial

CDT1 (NM_030928) Human Over-expression Lysate

Human

$628
Cat # LS081620
100 µg

Cdt1 Overview

Facts about DNA replication factor Cdt1.

DNA replication factor Cdt1 (Cdt1)

Required for both DNA replication and mitosis. DNA replication licensing factor, required for pre-replication complex assembly.

Cooperates with CDC6 and the origin recognition complex (ORC) during G1 phase of the cell cycle to promote the loading of the mini-chromosome maintenance (MCM) complex onto DNA to create pre-replication complexes (pre-RC). Required also for mitosis by promoting stable kinetochore-microtubule attachments (By similarity).

Gene Information

Mouse
Gene Name:	Cdt1
Uniprot:	Q8R4E9
Entrez:	67177

Family

Belongs to:

Cdt1 family

Alternative Names

chromatin licensing and DNA replication factor 1; DNA replication factor Cdt1; Double parked homolog; Double parked, Drosophila, homolog of; DUPRIS2

Molecular Weight

Mass (kDA):
61.51 kDA

Genomic Context


Mouse

Location:	8\|8 E1
Sequence:	8;

Diseases

Malignant Neoplasms
Neoplasms
Genomic Instability
Cell Transformation, Neoplastic
Malignant Paraganglionic Neoplasm
Carcinoma
Retinoblastoma
Hyperplasia
Aneuploidy
Polyploidy
Carcinogenesis
Ear, Patella, Short Stature Syndrome

Malignant Neoplasm Of Breast
Cytomegalovirus Infections
Mammary Neoplasms
Endoreduplication
Dwarfism
Lymphoma
Cytogenetic Abnormality

Pathways

Dna Replication
Cell Cycle
S Phase
Mitosis
Proteolysis
G1 Phase
Cell Division
Cell Proliferation
Dna Replication Initiation
Regulation Of Dna Replication
Localization
Cell Death
G2 Phase

Cell Cycle Arrest
Dna Repair
Pathogenesis
Cell Growth
Dna Damage Checkpoint
Metaphase
M Phase

PTMs

Phosphorylation
Ubiquitination
Methylation
Cleavage

Acetylation
Sumoylation
Dephosphorylation
Deacetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Cdt1

References

PMID: 11850834 by Arentson E., et al. Oncogenic potential of the DNA replication licensing protein CDT1.

PMID: 12192004 by Yanagi K., et al. Mouse geminin inhibits not only Cdt1-MCM6 interactions but also a novel intrinsic Cdt1 DNA binding activity.