Cdnf Antibodies

Cerebral dopamine neurotrophic factor (Cdnf)

Trophic factor for dopamine neurons. Prevents the 6- hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons.

When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra (By similarity). .

Gene Information

Mouse
Gene Name:	Cdnf
Uniprot:	Q8CC36
Entrez:	227526

Family

Belongs to:
ARMET family

Alternative Names

arginine-rich, mutated in early stage tumors-like 1; ARMETL1; ARMET-like protein 1; CDNF; cerebral dopamine neurotrophic factor; Conserved dopamine neurotrophic factor

Molecular Weight

Mass (kDA):
21.032 kDA

Genomic Context

Mouse
Location:	2|2 A1
Sequence:	2;

Tissue Specificity

Expressed at high levels in the heart, skeletal muscle, testis and brain (at protein level). In the brain, detected in the cerebral cortex neurons through layers II to VI. In the hippocampus, detected in the CA1 to CA3 pyramidal regions and in the granule and polymorph layers of dentate gyrus. Weak expression in the striatum. In substantia nigra, detected in solitary cells that did not express tyrosine hydroxylase, a marker for dopaminergic neurons. Relatively high expression in the Purkinje cells of the cerebellum and in regions of the brain stem, including the locus coeruleus.

Diseases

• Parkinson Disease
• Neurodegenerative Disorders
• Nervousness
• Secondary Parkinson Disease
• Physiological Stress
• Abnormal Degeneration
• Nerve Degeneration
• Inflammation
• Cholangiocarcinoma
• Sclerosis
• Brain Ischemia
• Primary Lateral Sclerosis

• Tetanus
• Glioma
• Amyotrophic Lateral Sclerosis
• Endoplasmic Reticulum Stress
• Dysplasia
• Metaphyseal Chondrodysplasia

Pathways

• Neuroprotection
• Pathogenesis
• Secretion
• Transport
• Glycosylation
• Localization
• Spermatogenesis
• Chondrocyte Proliferation
• Cell Death

• Protein Folding
• Pachytene
• Exocytosis
• Rna Interference

PTMs

• Phosphorylation

• Nitration

• Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Cdnf

Boster Bio - Best Uses Of The CDNF Marker

This article discusses Boster’s high affinity primary antibodies (and their CDNF markers). We will also examine Steven Boster’s life and learn how these antibodies as well as CDNF markers work in research. This marker is extremely useful for studying the immune reaction to cancer cells. What antibodies and markers are best for cancer research?

Boster has high-affinity prima antibodies

The CDNF marker is a high-expressing protein that regulates neuronal activity within the brain. Boster Bio offers high-affinity primary antibodies against this marker to help scientists detect this protein in cell culture and other biological assays. These antibodies have been validated using immunohistochemistry, ELISA, and Western Blotting methods. Boster Bio has a variety antibodies that you can choose from to make sure your next experiment is as efficient and reliable.

These monoclonal antibodies can be made using a unique process which uses the immune system of the host to identify antigens. They are called primary antibodies because they bind to a specific antigen in a specific way. Two important properties make primary antibodies unique. First, they must possess high affinity. However, high specificity is indicative of low-affinity. They should not bind with unintended or unwanted antigens. They should be able measure, purify, or detect the antigen they are interested in.

Boster offers a CDNF marker

Boster has a CDNF marker that is available to the public. CDNF is neurotrophic peptide that promotes survival midbrain dopaminergic cells, which are affected by Parkinson's disease. This peptide is not able to cross the blood-brain border and is therefore delivered directly to the brain via a surgically placed delivery device. The boster CDNF marker is one of many available antibodies for this gene.

History of Steven Boster

You're in the right place if you want to know more about Steven Boster’s history. This page contains all public records about Steven Boster. These include his current home address, previous addresses, and mobile phone numbers. You can also find out about Steve's friends and family. You can search for his name, state, and filter by age and gender.

Steve Boster, who was born in Joliet IL, died Sunday 26 June 2022. He was born in Joliet, IL. He was a former manager of retail sales and a Concordia Hall member. Frances of Verona in WI, his two daughters Crystal Boster (and Natosha) and 6 Grandchildren and 4 Brothers, Jack Boster & Sandra Blanton, are his surviving relatives. Lisa Milton is his niece and nephew.