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Cadherin-5 Antibodies
AND CDH5 ELISA kits, Cadherin-5 Proteins
Many biological assays use antibodies to detect Cadherin-5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cadherin-5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cadherin-5 antibodies...
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CDH5 Infographic by Boster Bio
All CDH5 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # EK1317
96 wells/kit, with removable strips.
Cat # EK1317
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # EK1318
96 wells/kit, with removable strips.
Cat # EK1318
96 wells/kit, with removable strips.
Anti-VE-Cadherin CDH5-Antibody Picoband®
5 Citations 8 Q&As
Human, Mouse, Rat
IHC, WB
$370
Cat # PA2079
100 μg/vial
Cat # PA2079
100 μg/vial
Anti-VE-Cadherin Cdh5-Rabbit Monoclonal Antibody
1 Citations
Mouse
IP, IF, ICC, WB
$370
Cat # M02632
100 μl
Cat # M02632
100 μl
Anti-VE-Cadherin CDH5 Antibody Picoband®
5 Citations
Human
ELISA, Flow Cytometry, IF, IHC, WB
$370
Cat # A02632-1
100 μg/vial
Cat # A02632-1
100 μg/vial
Anti-VE-Cadherin Cdh5-Antibody Picoband®
12 Citations
Mouse, Rat
ELISA, IHC, WB
$370
Cat # A02632-2
100 μg/vial
Cat # A02632-2
100 μg/vial
Mouse
ELISA
$500
Cat # EZ1318
For 5 plates, 96 wells each
Cat # EZ1318
For 5 plates, 96 wells each
Rat VE-Cadherin Cdh5 ELISA Kit PicoKine®
1 Citations 7 Q&As
Rat
ELISA
$499
Cat # EK1916
96 wells/kit, with removable strips.
Cat # EK1916
96 wells/kit, with removable strips.
Human
Flow Cytometry
$515
Cat # M02632-Dyl488
100 μg/vial
Cat # M02632-Dyl488
100 μg/vial
Human
Flow Cytometry, IP, IHC-F, ICC, WB
$299
Cat # M02632-1
0.1 mg
Cat # M02632-1
0.1 mg
Anti-VE-Cadherin CDH5-Monoclonal Antibody
2 Citations
Human, Mouse, Rat
ELISA, WB
$380
Cat # M02632-3
100ul
Cat # M02632-3
100ul
CDH5 Overview
Facts about Cadherin-5.
Cadherin-5 (CDH5)
They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a essential role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions.
It partners with alpha-catenin forming a link to the cytoskeleton. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen.
Gene Information
| Human | |
|---|---|
| Gene Name: | CDH5 |
| Uniprot: | P33151 |
| Entrez: | 1003 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
7B4 antigen; 7B4; cadherin 5, type 2 (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular epithelium); Cadherin-5; CD144 antigen; CD144; CDH5; endothelial-specific cadherin; FLJ17376; Vascular endothelial cadherin; VECadherin; VE-Cadherin
Molecular Weight
Mass (kDA):
87.528 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 16q21 |
| Sequence: | 16; NC_000016.10 (66366657..66404784) |
Tissue Specificity
Endothelial tissues and brain.
Subcellular Localizations
Cell junction. Cell membrane; Single-pass type I membrane protein. Found at cell-cell boundaries and probably at cell-matrix boundaries. KRIT1 and CDH5 reciprocally regulate their localization to endothelial cell-cell junctions.
Diseases
- Tumor Angiogenesis
- Neoplasms
- Malignant Neoplasms
- Tissue Adhesions
- Carcinoma
- Pathologic Neovascularization
- Carcinogenesis
- Neoplasm Metastasis
- Hemorrhage
- Inflammation
- Acute Myocardial Infarction
- Infarction
Interacting Proteins
- CTNNB1
- PARD3
- PARD6A
- WARS
Pathways
- Angiogenesis
- Cell Adhesion
- Reverse Transcription
- Transdifferentiation
- Methylation
- Regulation Of Angiogenesis
- Cell Activation
- Tube Formation
- Glucose Homeostasis
- Translation
- Cell Cycle
- Cell Differentiation
- Regionalization
PTMs
- Methylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CDH5
bosterbio.com/bosterbio-gene-info-cards/CDH5
References
PMID: 7627717 by Breviario F., et al. Functional properties of human vascular endothelial cadherin (7B4/cadherin-5), an endothelium-specific cadherin.
PMID: 9219219 by Ali J., et al. Vascular endothelial cadherin (VE-cadherin): cloning and role in endothelial cell-cell adhesion.
16 Publications of Boster Cadherin-5 Antibodies & ELISA Kits
- PubMed ID: 10.7150/ijbs.29009, Metformin Promotes the Survival of Random-Pattern Skin Flaps by Inducing Autopha...
- PubMed ID: 10.3389/fphar.2020.612932, Butylphthalide Inhibits Autophagy and Promotes Multiterritory Perforator Flap Su...
- PubMed ID: 10.3389/fphar.2018.01178, Salvianolic Acid B Promotes the Survival of Random-Pattern Skin Flaps in Rats by...
- PubMed ID: 10.3389/fcell.2021.643996, Targeting TFE3 Protects Against Lysosomal Malfunction-Induced Pyroptosis in Rand...
- PubMed ID: 10.2147/DDDT.S195479, Therapeutic potential of pravastatin for random skin flaps necrosis: involvement...
- PubMed ID: 10.1139/cjpp-2014-0169, Protective effect of co-administration of rosuvastatin and probucol on atheroscl...
- PubMed ID: 10.1089/scd.2019.0198, The Regulatory Effect of VEGF-Ax on Rat Bone Marrow Mesenchymal Stem Cells Angio...
- PubMed ID: 10.1038/s41419-019-2105-0, FGF21 augments autophagy in random-pattern skin flaps via AMPK signaling pathway...
- PubMed ID: 10.1016/j.jstrokecerebrovasdis.2020.104748, Effect of MicroRNA-126a-3p on Bone Marrow Mesenchymal Stem Cells Repairing Blood...
- PubMed ID: -, Zhou F,Zhang X,Jiang L,Li S,Chen Y and Wu J(2021) Pseudoginsenoside F11 Enhances...
- PubMed ID: 33505583, Chen H,Chen B,Li B,Luo X,Wu H,Zhang C,Liu J,Jiang J,Zhao B. Gastrodin Promotes t...
- PubMed ID: 32913550, Zhang C,Shao Z,Chen Z,Lin C,Hu S,Lou Z,Li J,Zheng X,Lin N,Gao W.Hydroxysafflor y...
- PubMed ID: 33044023, Li J,Chen H,Lou J,Bao G,Wu C,Lou Z,Wang X,Ding J,Li Z,Xiao J,Xu H,Gao W,Zhou K.E...
- PubMed ID: 30745824, Metformin Promotes the Survival of Random-Pattern Skin Flaps by Inducing Autopha...
- PubMed ID: 28808419, Exposure to Concentrated Ambient Fine Particulate Matter Induces Vascular Endoth...
- PubMed ID: 25337216, Liu Y, Zhu Z, Xiong Z, Zheng J, Hu Z, Qiu J. Int J Clin Exp Pathol. 2014 Aug 15;...
*More publications can be found for each product on its corresponding product page