CD70 antigen Antibodies

AND CD70 ELISA kits, CD70 antigen Proteins

Many biological assays use antibodies to detect CD70 antigen, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CD70 antigen in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CD70 antigen antibodies...

We validate the specificity of these antibodies to CD70 antigen by testing them on tissues known to express CD70 positively and negatively. Browse below to find the CD70 antibody that suites your experiment. We have 9 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CD70 Infographic by Boster Bio

All CD70 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Mouse CD70/TNFSF7/cd27L ELISA Kit PicoKine®

9 Q&As

Mouse

ELISA

$499
Cat # EK1310
96 wells/kit, with removable strips.

Anti-CD70/Cd27L Antibody

7 Q&As

Human

$360
Cat # A02853
100 µl

Anti-CD70 antigen CD70 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A02853-1
100ul

CD70 (NM_001252) Human Recombinant Protein

$1249
Cat # PROTP32970
20 µg

Anti-CD70 Mouse Monoclonal Antibody [Clone ID: OTI7B2]

Human

Flow Cytometry

$523
Cat # M02853
100 µl

Anti-Cd70 Antibody Picoband®

Mouse, Rat

ELISA, IHC, WB

$370
Cat # A02853-2
100 μg/vial

CD70 (NM_001252) Human Over-expression Lysate

Human

$628
Cat # LS000970
100 µg

Human recombinant CD27L (CD27 ligand) protein, AF

Human

Cell Culture

$77
Cat # PROTP32970-5
5ug,20ug,100ug,500ug,1mg

Mouse recombinant CD27L (CD27 ligand) protein, AF

Mouse

Cell Culture

$77
Cat # PROTO55237
5ug,20ug,100ug,500ug,1mg

CD70 Overview

Facts about CD70 antigen.

CD70 3D structure. Source: alphafold

CD70 antigen (CD70)

Cytokine that binds to CD27. Plays a role in T-cell activation.

Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. .

Gene Information

Human
Gene Name:	CD70
Uniprot:	P32970
Entrez:	970

Family

Belongs to:

tumor necrosis factor family

Alternative Names

CD27 Ligand; CD27-L; CD27LCD27 ligand; CD27LG; CD70 molecule; CD70; Ki-24 antigen; surface antigen CD70; TNFSF7; TNFSF7CD70 antigen; tumor necrosis factor (ligand) superfamily, member 7; Tumor necrosis factor ligand superfamily member 7

Molecular Weight

Mass (kDA):
21.118 kDA

Genomic Context


Human

Location:	19p13.3
Sequence:	19; NC_000019.10 (6581648..6591150, complement)

Subcellular Localizations

Membrane; Single-pass type II membrane protein.

Diseases

Neoplasms
Malignant Neoplasms
Lymphoma
Carcinoma
Lupus Erythematosus, Systemic
Autoimmune Reaction
Inflammation
Leukemia
Virus Diseases
Immunologic Deficiency Syndromes
Malignant Paraganglionic Neoplasm
Autoimmune Diseases
Hiv Infections

Melanoma
Renal Cell Carcinoma
Autoimmunity
Influenza
Kidney Neoplasm
Infective Disorder
Neoplasm Metastasis

Pathways

Cell Activation
Cell Proliferation
Secretion
Immune Response
Pathogenesis
T Cell Activation
Methylation
T Cell Proliferation
Demethylation
Dna Methylation
Cell Differentiation
B Cell Activation
Cytokine Production

Dna Hypomethylation
Cell Development
T Cell Differentiation
Dna Demethylation
B Cell Proliferation
Cell Growth
Lymphocyte Activation

PTMs

Methylation
Demethylation
Phosphorylation
Cleavage

Acetylation
Glycosylation
Reduction
Deacetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CD70

References

PMID: 8387892 by Goodwin R.G., et al. Molecular and biological characterization of a ligand for CD27 defines a new family of cytokines with homology to tumor necrosis factor.

PMID: 8120384 by Bowman M.R., et al. The cloning of CD70 and its identification as the ligand for CD27.