Caprin-1 Antibodies

AND CAPRIN1 ELISA kits, Caprin-1 Proteins

Many biological assays use antibodies to detect Caprin-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Caprin-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Caprin-1 antibodies...

We validate the specificity of these antibodies to Caprin-1 by testing them on tissues known to express CAPRIN1 positively and negatively. Browse below to find the CAPRIN1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CAPRIN1 Infographic by Boster Bio

All CAPRIN1 Products

Product

Figures

Specificity

Applications

Price

Anti-Caprin-1 CAPRIN1 Antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A05178
100ul

GPIP137 (CAPRIN1) (NM_005898) Human Over-expression Lysate

Human

$628
Cat # LS004076
100 µg

CAPRIN1 Overview

Facts about Caprin-1.

CAPRIN1 3D structure. Source: alphafold

Caprin-1 (CAPRIN1)

May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Binds directly and selectively to MYC and CCND2 RNAs.

In neuronal cells, directly binds to several mRNAs related to RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, and to GRIN1 and KPNB1 mRNAs, but not to rRNAs. .

Gene Information

Human
Gene Name:	CAPRIN1
Uniprot:	Q14444
Entrez:	4076

Family

Belongs to:

caprin family

Alternative Names

activation/proliferation-associated protein 1; caprin 1; caprin-1; cell cycle associated protein 1; Cell cycle-associated protein 1; Cytoplasmic activation- and proliferation-associated protein 1; cytoplasmic activation/proliferation-associated protein-1; GPI-anchored membrane protein 1GPIP137; GPI-p137; M11S1GPI-anchored protein p137; Membrane component chromosome 11 surface marker 1; membrane component, chromosome 11, surface marker 1; p137GPI; RNA granule protein 105; RNG105GPIAP1

Molecular Weight

Mass (kDA):
78.366 kDA

Genomic Context


Human

Location:	11p13
Sequence:	11; NC_000011.10 (34051663..34102610)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Cytoplasm, cytosol. Cell projection, dendrite. Associated with RNA granules.

Diseases

Vaccinia
Smallpox
Paroxysmal Nocturnal Hemoglobinuria
Neoplasms
Hemoglobinuria
Hemoglobinuria, Paroxysmal
Anemia
Thrombosis
Hyperplasia
Neurodegenerative Disorders
Pancytopenia
Vascular Occlusion

Venous Thrombosis
Intravascular Hemolysis
Hemolysis (disorder)
Aplastic Anemia
Peripheral Circulatory Failure
Monocytic Leukemia

Pathways

Translation
Cell Cycle
Dna Replication
Transport
Response To Stress
Cell Proliferation
Interaction With Host
G1 Phase
Immune Response
Localization
Cell Cycle Arrest

Rna Splicing
Cytokine Production
Cell Death
Cellular Response To Stress
Regulation Of Translation
Pathogenesis

PTMs

Phosphorylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CAPRIN1

References

PMID: 7657653 by Ellis J.A., et al. Identification and characterization of a novel protein (p137) which transcytoses bidirectionally in Caco-2 cells.

PMID: 8786113 by Gessler M., et al. The gene encoding the GPI-anchored membrane protein p137GPI (M11S1) maps to human chromosome 11p13 and is highly conserved in the mouse.