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- Table of Contents
Facts about Calmodulin-1.
Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (PubMed:16760425). Mediates calcium-dependent inactivation of CACNA1C (PubMed:26969752).
Human | |
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Gene Name: | CALM1 |
Uniprot: | P0DP23 |
Entrez: | 801 |
Belongs to: |
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calmodulin family |
CALM; CALM1; CALM2; CALM3; CALML2; calmodulin 1 (phosphorylase kinase, delta); Calmodulin 1; calmodulin; CaM; CAM1; CAM2; CAM3; CAMB; CAMC; CAMI; CAMIII; CPVT4; DD132; PHKDCAM; phosphorylase kinase, delta subunit
Mass (kDA):
16.838 kDA
Human | |
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Location: | 14q32.11 |
Sequence: | 14; NC_000014.9 (90396502..90408275) |
Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Distributed throughout the cell during interphase, but during mitosis becomes dramatically localized to the spindle poles and the spindle microtubules.
PMID: 6385987 by Wawrzynczak E.J., et al. Isolation and nucleotide sequence of a cDNA encoding human calmodulin.
PMID: 7925473 by Rhyner J.A., et al. Structure of the human CALM1 calmodulin gene and identification of two CALM1-related pseudogenes CALM1P1 and CALM1P2.