Cytohesin-2 Antibodies

AND CYTH2 ELISA kits, Cytohesin-2 Proteins

Many biological assays use antibodies to detect Cytohesin-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cytohesin-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cytohesin-2 antibodies...

We validate the specificity of these antibodies to Cytohesin-2 by testing them on tissues known to express CYTH2 positively and negatively. Browse below to find the CYTH2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CYTH2 Infographic by Boster Bio

All CYTH2 Products

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Product

Figures

Specificity

Applications

Price

Cytohesin 2 (CYTH2) (NM_017457) Human Recombinant Protein

$813
Cat # PROTQ99418
20 µg

Anti-Cytohesin 2 (CYTH2) Mouse Monoclonal Antibody [Clone ID: OTI4D9]

Human, Mouse, Rat

IHC, WB

$523
Cat # M08775
100 µl

Cytohesin 2 (CYTH2) (NM_017457) Human Over-expression Lysate

Human

$628
Cat # LS009266
100 µg

CYTH2 Overview

Facts about Cytohesin-2.

CYTH2 3D structure. Source: alphafold

Cytohesin-2 (CYTH2)

Acts as a guanine-nucleotide exchange factor (GEF). Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6.

Activates ARF factors through replacement of GDP with GTP (By similarity). The cell membrane form, in association with ARL4 proteins, recruits ARF6 to the plasma membrane (PubMed:17398095).

Gene Information

Human
Gene Name:	CYTH2
Uniprot:	Q99418
Entrez:	9266

Family

Belongs to:

No superfamily

Alternative Names

ARF exchange factor; ARF nucleotide-binding site opener; ARNOPH, SEC7 and coiled-coil domain-containing protein 2; CTS18.1; cytohesin 2; pleckstrin homology, Sec7 and coiled-coil domains 2 (cytohesin-2); Protein ARNO; PSCD2LCTS18; PSCD2pleckstrin homology, Sec7 and coiled-coil domains 2; Sec7 and coiled/coil domains 2 (cytohesin-2)

Molecular Weight

Mass (kDA):
46.546 kDA

Genomic Context


Human

Location:	19q13.33
Sequence:	19; NC_000019.10 (48469208..48482314)

Tissue Specificity

Widely expressed.

Subcellular Localizations

Cell membrane; Peripheral membrane protein. Cytoplasm. Cell projection. Cell projection, growth cone. Cell junction, tight junction. Cell junction, adherens junction. Both isoform 1 and isoform 2 are recruited to the cell membrane through its association with ARL4A, ARL4C and ARL4D. They require also interaction with phosphoinositides for targeting to plasma membrane (PubMed:17398095). In differentiating neuroblastoma cells, colocalizes with CCDC120 in both neurite shaft and growth cone areas.