Cytohesin-1 Antibodies

AND CYTH1 ELISA kits, Cytohesin-1 Proteins

Many biological assays use antibodies to detect Cytohesin-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cytohesin-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cytohesin-1 antibodies...

We validate the specificity of these antibodies to Cytohesin-1 by testing them on tissues known to express CYTH1 positively and negatively. Browse below to find the CYTH1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CYTH1 Infographic by Boster Bio

All CYTH1 Products

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Product

Figures

Specificity

Applications

Price

Anti-Cytohesin-1 CYTH1 Antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A10889
100ul

Human Cytohesin-1 Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ15438
Starting from 20ug

Cytohesin 1 (CYTH1) (NM_004762) Human Over-expression Lysate

Human

$628
Cat # LS009267
100 µg

CYTH1 Overview

Facts about Cytohesin-1.

CYTH1 3D structure. Source: alphafold

Cytohesin-1 (CYTH1)

Promotes guanine-nucleotide exchange on ARF1, ARF5 and ARF6.
Promotes the activation of ARF factors through replacement of GDP with GTP.

Plays an essential role in membrane trafficking, during junctional remodeling and epithelial polarization, through regulation of ARF6 activity. .

Gene Information

Human
Gene Name:	CYTH1
Uniprot:	Q15438
Entrez:	9267

Family

Belongs to:

No superfamily

Alternative Names

B2-1; CYTH1; cytoadhesin 1; cytohesin 1; Cytohesin1; Cytohesin-1; D17S811ECYTOHESIN-1; FLJ34050; FLJ41900; homolog of secretory protein SEC7; PH, SEC7 and coiled-coil domain-containing protein 1; pleckstrin homology, Sec7 and coiled-coil domains 1; PSCD1; SEC7 homolog B2-1; SEC7

Molecular Weight

Mass (kDA):
46.413 kDA

Genomic Context


Human

Location:	17q25.3
Sequence:	17; NC_000017.11 (78674047..78782342, complement)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Cell membrane; Peripheral membrane protein. Cytoplasm, cytosol. Cell junction, tight junction. Cell junction, adherens junction. Colocalized with TJP1 during epithelial polarization.

Diseases

Myopathy
Premature Obstetric Labor
Hereditary Diseases
Pregnancy Complications
Impairment (finding)
Connective Tissue Diseases

Interacting Proteins

CCDC120
CNKSR1
CYTIP
INAVA
IPCEF1

PTMs

Ribosylation

Research Areas

Membrane Trafficking and Chaperones

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CYTH1

References

PMID: 1511013 by Liu L., et al. Cloning and sequencing of a human cDNA from cytolytic NK/T cells with homology to yeast SEC7.

PMID: 10652308 by Ogasawara M., et al. Similarities in function and gene structure of cytohesin-4 and cytohesin-1, guanine nucleotide-exchange proteins for ADP-ribosylation factors.