CYP51A1 Antibodies

AND CYP51A1 ELISA kits, CYP51A1 Proteins

Many biological assays use antibodies to detect CYP51A1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CYP51A1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CYP51A1 antibodies...

We validate the specificity of these antibodies to CYP51A1 by testing them on tissues known to express CYP51A1 positively and negatively. Browse below to find the CYP51A1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CYP51A1 Infographic by Boster Bio

All CYP51A1 Products

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Product

Figures

Specificity

Applications

Price

Anti-CP51A CYP51A1 Antibody

Human

ELISA, WB

$380
Cat # A04032
100ul

Anti-CYP51A1/CYP51 Antibody Picoband®

Human, Monkey, Mouse

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A04032-1
100 μg/vial

CYP51A1 (NM_000786) Human Recombinant Protein

$1062
Cat # PROTQ16850
20 µg

Anti-CYP51A1 Antibody (Center)

Human

Flow Cytometry, IHC-P, WB

$299
Cat # A04032-2
80 µl

CYP51A1 Overview

Facts about Lanosterol 14-alpha demethylase.

CYP51A1 3D structure. Source: alphafold

Lanosterol 14-alpha demethylase (CYP51A1)

Catalyzes C14-demethylation of lanosterol; it transforms lanosterol to 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol. .

Gene Information

Human
Gene Name:	CYP51A1
Uniprot:	Q16850
Entrez:	1595

Family

Belongs to:

cytochrome P450 family

Alternative Names

CP51; CYP51Cytochrome P450LI; CYPL1; CYPLI; Cytochrome P450 51A1; cytochrome P450, family 51, subfamily A, polypeptide 1; Cytochrome P450-14DM; EC 1.14.13.70; lanosterol 14-alpha demethylase; lanosterol 14-alpha-demethylase; LDMCytochrome P45014DM; P450-14DM; P450L1,51 (lanosterol 14-alpha-demethylase); Sterol 14-alpha demethylase

Molecular Weight

Mass (kDA):
56.806 kDA

Genomic Context


Human

Location:	7q21.2
Sequence:	7; NC_000007.14 (92112149..92134745, complement)

Tissue Specificity

Ubiquitously expressed with highest levels in testis, ovary, adrenal, prostate, liver, kidney and lung.

Subcellular Localizations

Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein.

Diseases

Tuberculosis
Candidiasis
Infective Disorder
Mycoses
Acquired Immunodeficiency Syndrome
Infection By Cryptococcus Neoformans
Malignant Neoplasms
Neoplasms
Liver Carcinoma
Chagas Disease
Aids-related Opportunistic Infections
Opportunistic Infections
Oropharyngeal Disorders

Hiv Infections
Immunologic Deficiency Syndromes
Atherosclerosis
Oropharyngeal Candidiasis
Growth Arrest
Candidemia
Neonatal Torulopsis Glabrata Fungemia

Pathways

Meiosis
Cell Cycle
Transport
Spermatogenesis
Demethylation
Cell Proliferation
Oocyte Maturation
Cell Growth
Fertilization
Translation
G1 Phase
Ovulation
Localization

Drug Resistance
Cholesterol Homeostasis
Secretion
Electron Transport
Vasculogenesis
Endothelial Cell Proliferation
Cytokinesis

PTMs

Demethylation
Phosphorylation

Reduction
Hydroxylation

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CYP51A1

References

PMID: 8619637 by Stroemstedt M., et al. The ubiquitously expressed human CYP51 encodes lanosterol 14 alpha- demethylase, a cytochrome P450 whose expression is regulated by oxysterols.

PMID: 8797093 by Aoyama Y., et al. Sterol 14-demethylase P450 (P45014DM*) is one of the most ancient and conserved P450 species.