Cytochrome P450 2A13 Antibodies

AND CYP2A13 ELISA kits, Cytochrome P450 2A13 Proteins

Many biological assays use antibodies to detect Cytochrome P450 2A13, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cytochrome P450 2A13 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cytochrome P450 2A13 antibodies...

We validate the specificity of these antibodies to Cytochrome P450 2A13 by testing them on tissues known to express CYP2A13 positively and negatively. Browse below to find the CYP2A13 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CYP2A13 Infographic by Boster Bio

All CYP2A13 Products

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Anti-Cytochrome P450 2A13 CYP2A13 Antibody

13 Q&As

Human

$360
Cat # A04468
100 µl

Anti-CYP2A13 (N338) Antibody

Human

IF, IHC

$405
Cat # A04468-1
100ul

CYP2A13 Overview

Facts about Cytochrome P450 2A13.

CYP2A13 3D structure. Source: alphafold

Cytochrome P450 2A13 (CYP2A13)

Exhibits a coumarin 7-hydroxylase action. Active in the metabolic activation of hexamethylphosphoramide, N,N- dimethylaniline, 2'-methoxyacetophenone, N- nitrosomethylphenylamine, as well as the tobacco-specific carcinogen, 4- (methylnitrosamino)-1-(3-pyridyl)-1-butanone.

Possesses phenacetin O-deethylation action. .

Gene Information

Human
Gene Name:	CYP2A13
Uniprot:	Q16696
Entrez:	1553

Family

Belongs to:

cytochrome P450 family

Alternative Names

CPAD; CYP2A; CYPIIA13; cytochrome P450 2A13; cytochrome P450, family 2, subfamily A, polypeptide 13; cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 13; EC 1.14.14.1

Molecular Weight

Mass (kDA):
56.688 kDA

Genomic Context


Human

Location:	19q13.2
Sequence:	19; NC_000019.10 (41088451..41096195)

Tissue Specificity

Expressed in liver and a number of extrahepatic tissues, including nasal mucosa, lung, trachea, brain, mammary gland, prostate, testis, and uterus, but not in heart, kidney, bone marrow, colon, small intestine, spleen, stomach, thymus, or skeletal muscle.

Subcellular Localizations

Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.

Diseases

Malignant Neoplasms
Malignant Neoplasm Of Lung
Lung Neoplasms
Neoplasms
Carcinogenesis
Carcinoma
Cell Transformation, Neoplastic
Malignant Squamous Cell Neoplasm
Adenocarcinoma
Head And Neck Neoplasms
Malignant Neck Neoplasm
Malignant Head And Neck Neoplasm
Cholangiocarcinoma

Malignant Neoplasm Of Urinary Bladder
Mouth Neoplasms
Dysequilibrium Syndrome
Non-small Cell Lung Carcinoma
Diabetes Mellitus
Cancer Patients And Suicide And Depression
Small Cell Carcinoma Of Lung

Pathways

Conjugation
Methylation
Transport
Histone Deacetylation
Aging
Dna Demethylation
Demethylation
Dna Replication
Dna Amplification
Translation
Cell Death

Cell Cycle
Fibrinolysis
Protein Digestion
Cell Growth
Pathogenesis
Regulation Of Fibrinolysis

PTMs

Hydroxylation
Oxidation

Demethylation
Methylation

Deacetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CYP2A13

References

PMID: 7668294 by Fernandez-Salguero P., et al. A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A genes and identification of variant CYP2A6 alleles.

PMID: 11016631 by Su T., et al. Human cytochrome P450 CYP2A13: predominant expression in the respiratory tract and its high efficiency metabolic activation of a tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1- butanone.