CYBA Antibodies

AND CYBA ELISA kits, CYBA Proteins

Many biological assays use antibodies to detect CYBA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CYBA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CYBA antibodies...

We validate the specificity of these antibodies to CYBA by testing them on tissues known to express CYBA positively and negatively. Browse below to find the CYBA antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CYBA Infographic by Boster Bio

All CYBA Products

Product

Figures

Specificity

Applications

Price

Anti-p22-phox CYBA Antibody

1 Citations

Human, Mouse, Rat

$405
Cat # A03781
100ul

CYBA (NM_000101) Human Over-expression Lysate

Human

$628
Cat # LS001535
100 µg

CYBA Overview

Facts about Cytochrome b-245 light chain.

CYBA 3D structure. Source: alphafold

Cytochrome b-245 light chain (CYBA)

Critical part of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.

Gene Information

Human
Gene Name:	CYBA
Uniprot:	P13498
Entrez:	1535

Family

Belongs to:

p22phox family

Alternative Names

cytochrome b light chain; Cytochrome b(558) alpha chain; cytochrome b(558) alpha-subunit; cytochrome b, alpha polypeptide; cytochrome b-245 light chain; cytochrome b-245, alpha polypeptide; Cytochrome b558 subunit alpha; flavocytochrome b-558 alpha polypeptide; Neutrophil cytochrome b 22 kDa polypeptide; p22 phagocyte B-cytochrome; p22phox; p22-PHOX; Superoxide-generating NADPH oxidase light chain subunit

Molecular Weight

Mass (kDA):
21.013 kDA

Genomic Context


Human

Location:	16q24.2
Sequence:	16; NC_000016.10 (88643289..88651079, complement)

Subcellular Localizations

Cell membrane. As unassembled monomer may localize to the endoplasmic reticulum.

Diseases

Hypertensive Disease
Atherosclerosis
Granulomatous Disease, Chronic
Coronary Artery Disease
Cardiovascular Diseases
Granulomatous Disorder
Diabetes Mellitus
Cholangiocarcinoma
Inflammation
Coronary Heart Disease
Malignant Neoplasms
Diabetes Mellitus, Non-insulin-dependent

Kidney Diseases
Infarction
Neoplasms
Arteriosclerosis
Vascular Diseases
Myocardial Infarction

Interacting Proteins

NCF1
NOXO1

Pathways

Pathogenesis
Localization
Respiratory Burst
Cell Proliferation
Cell Growth
Immune Response
Vasodilation
Excretion
Translation
Phagocytosis
Cell Death
Glycosylation
Inflammatory Response

Aging
Angiogenesis
Cell Migration
Neutrophil Activation
Coagulation
Transport
Cell Cycle

PTMs

Phosphorylation
Glycosylation
Oxidation
Reduction
Cleavage

Biotinylation
Methylation
Hydroxylation
Deglycosylation
Ubiquitination

Iodination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CYBA

References

PMID: 3368442 by Parkos C.A., et al. Primary structure and unique expression of the 22-kilodalton light chain of human neutrophil cytochrome b.

PMID: 2243141 by Dinauer M.C., et al. Human neutrophil cytochrome b light chain (p22-phox). Gene structure, chromosomal location, and mutations in cytochrome-negative autosomal recessive chronic granulomatous disease.

1 Publications of Boster CYBA Antibodies & ELISA Kits

PubMed ID: 26648159, NADPH oxidase 3-associated oxidative stress and caspase 3-dependent apoptosis in...

*More publications can be found for each product on its corresponding product page