This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
1 Citations 7 Q&As
Facts about C-X-C motif chemokine 11.
Binds to CXCR3. May play an essential role in CNS diseases which involve T-cell recruitment.
Human | |
---|---|
Gene Name: | CXCL11 |
Uniprot: | O14625 |
Entrez: | 6373 |
Belongs to: |
---|
intercrine alpha (chemokine CxC) family |
beta-R1; b-R1; chemokine (C-X-C motif) ligand 11; CXCL11; H174; H174IP9; Interferon gamma-inducible protein 9; Interferon-inducible T-cell alpha chemoattractant; IP-9member 11; ITAC; I-TAC; I-TACMGC102770; SCYB9B; small inducible cytokine subfamily B (Cys-X-Cys), member 9B; Small-inducible cytokine B11
Mass (kDA):
10.365 kDA
Human | |
---|---|
Location: | 4q21.1 |
Sequence: | 4; NC_000004.12 (76033682..76036070, complement) |
High levels in peripheral blood leukocytes, pancreas and liver astrocytes. Moderate levels in thymus, spleen and lung. Low levels in placenta, prostate and small intestine. Also found in epidermal basal layer keratinocytes in skin disorders.
Secreted.
PMID: 8798467 by Rani M.R.S., et al. Characterization of beta-R1, a gene that is selectively induced by interferon beta (IFN-beta) compared with IFN-alpha.
PMID: 9370294 by Jacobs K.A., et al. A genetic selection for isolating cDNAs encoding secreted proteins.
*More publications can be found for each product on its corresponding product page