CWC22 Antibodies

AND CWC22 ELISA kits, CWC22 Proteins

Many biological assays use antibodies to detect CWC22, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CWC22 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CWC22 antibodies...

We validate the specificity of these antibodies to CWC22 by testing them on tissues known to express CWC22 positively and negatively. Browse below to find the CWC22 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CWC22 Infographic by Boster Bio

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CWC22 (NM_020943) Human Over-expression Lysate

Human

$628
Cat # LS057703
100 µg

CWC22 Overview

Facts about Pre-mRNA-splicing factor CWC22 homolog.

CWC22 3D structure. Source: alphafold

Pre-mRNA-splicing factor CWC22 homolog (CWC22)

Required for pre-mRNA splicing and for exon-junction complex (EJC) assembly. Hinders EIF4A3 from non-specifically binding RNA and escorts it to the splicing machinery to advertise EJC assembly on mature mRNAs.

Through its role in EJC assembly, required for nonsense-mediated mRNA decay. .

Gene Information

Human
Gene Name:	CWC22
Uniprot:	Q9HCG8
Entrez:	57703

Family

Belongs to:

CWC22 family

Alternative Names

CWC22 spliceosome-associated protein homolog (S. cerevisiae); EIF4GL; fSAPbpre-mRNA-splicing factor CWC22 homolog; KIAA1604NCMfunctional spliceosome-associated protein b; Nucampholin homolog

Molecular Weight

Mass (kDA):
105.466 kDA

Genomic Context


Human

Location:	2q31.3
Sequence:	2; NC_000002.12 (179944876..180007297, complement)

Subcellular Localizations

Nucleus. Nucleus speckle. Concentrates around speckles, which are sites of pre-mRNA synthesis and processing, where it colocalizes with EJC core proteins.