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- Table of Contents
Facts about Dipeptidyl peptidase 1.
Active against a broad assortment of dipeptide substrates composed of both polar and hydrophobic amino acids. Proline cannot occupy the P1 position and arginine cannot occupy the P2 position of the substrate.
Human | |
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Gene Name: | CTSC |
Uniprot: | P53634 |
Entrez: | 1075 |
Belongs to: |
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peptidase C1 family |
Cathepsin C; cathepsin CEC 3.4.14.1; Cathepsin J; CPPIHMS; CTSC; dipeptidyl peptidase 1; Dipeptidyl peptidase I; Dipeptidyl transferase; dipeptidyl-peptidase I; DPP1; DPPI; DPP-I; JP; JPD; PALS; PLS
Mass (kDA):
51.854 kDA
Human | |
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Location: | 11q14.2 |
Sequence: | 11; NC_000011.10 (88293592..88337736, complement) |
Ubiquitous. Highly expressed in lung, kidney and placenta. Detected at intermediate levels in colon, small intestine, spleen and pancreas.
Lysosome.
PMID: 7649281 by Paris A., et al. Molecular cloning and sequence analysis of human preprocathepsin C.
PMID: 9092576 by Rao N.V., et al. Human dipeptidyl-peptidase I. Gene characterization, localization, and expression.