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- Table of Contents
Facts about C-terminal-binding protein 1.
Involved in controlling the balance between tubular and piled structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation.
Human | |
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Gene Name: | CTBP1 |
Uniprot: | Q13363 |
Entrez: | 1487 |
Belongs to: |
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D-isomer specific 2-hydroxyacid dehydrogenase family |
BARS; brefeldin A-ribosylated substrate; CTBP; CtBP1; C-terminal binding protein 1; C-terminal-binding protein 1; EC 1.1.1; EC 1.1.1.-; EC 1.1.1.158; MGC104684
Mass (kDA):
47.535 kDA
Human | |
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Location: | 4p16.3 |
Sequence: | 4; NC_000004.12 (1211444..1250355, complement) |
Expressed in germinal center B-cells.
Cytoplasm. Nucleus.
PMID: 7479821 by Schaeper U., et al. Molecular cloning and characterization of a cellular phosphoprotein that interacts with a conserved C-terminal domain of adenovirus E1A involved in negative modulation of oncogenic transformation.
PMID: 9858600 by Sewalt R.G.A.B., et al. C-terminal binding protein is a transcriptional repressor that interacts with a specific class of vertebrate polycomb proteins.