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- Table of Contents
Facts about Cancer/testis antigen 1.
Human | |
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Gene Name: | CTAG1A |
Uniprot: | P78358 |
Entrez: | 246100 |
Belongs to: |
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CTAG/PCC1 family |
CTAG1A cancer/testis antigen 1A; ESO1; LAGE2A
Mass (kDA):
17.992 kDA
Human | |
---|---|
Location: | Xq28 |
Sequence: | X; NC_000023.11 (154585133..154586816) |
Expressed in testis and ovary and in a wide variety of cancers. Detected in uterine myometrium. Expressed from 18 weeks until birth in human fetal testis. In the adult testis, is strongly expressed in spermatogonia and in primary spermatocytes, but not in post-meiotic cells or in testicular somatic cells (at protein level).
Cytoplasm.
PMID: 9050879 by Chen Y.-T., et al. A testicular antigen aberrantly expressed in human cancers detected by autologous antibody screening.
PMID: 9626360 by Lethe B.G., et al. LAGE-1, a new gene with tumor specificity.