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CSF2RB Antibodies
AND CSF2RB ELISA kits, CSF2RB Proteins
Many biological assays use antibodies to detect CSF2RB, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CSF2RB in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CSF2RB antibodies...
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CSF2RB Infographic by Boster Bio
All CSF2RB Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA
$480
Cat # EKC1299
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1299
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2046
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2046
1 kit, containing two 96-well plates and all necessary reagents
Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A02219-3
100 μg/vial
Cat # A02219-3
100 μg/vial
Human, Mouse, Rat
ELISA, IHC, WB
$380
Cat # A02219Y593
100ul
Cat # A02219Y593
100ul
Human
IHC, WB
$523
Cat # M02219
100 µl
Cat # M02219
100 µl
CSF2RB Overview
Facts about Cytokine receptor common subunit beta.
Cytokine receptor common subunit beta (CSF2RB)
High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CSF2RB |
| Uniprot: | P32927 |
| Entrez: | 1439 |
Family
| Belongs to: |
|---|
| type I cytokine receptor family |
Alternative Names
beta, low-affinity; CD131 antigen; CD131; CDw131; colony stimulating factor 2 receptor, beta, low-affinity(granulocyte-macrophage); Common beta Chain; CSF2RB; cytokine receptor common subunit beta; GM-CSF R beta; GM-CSF/IL-3/IL-5 receptor common beta subunit; GM-CSF/IL-3/IL-5 receptor common beta-chain; IL-3 R beta; IL3RB; IL-5 R beta; interleukin 3 receptor/granulocyte-macrophage colony stimulating factor 3receptor, beta (high affinity)
Molecular Weight
Mass (kDA):
97.336 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 22q12.3 |
| Sequence: | 22; NC_000022.11 (36913574..36940449) |
Subcellular Localizations
Membrane; Single-pass type I membrane protein.
Diseases
- Schizophrenia
- Malignant Neoplasms
- Leukemia
- Myeloid Leukemia
- Pulmonary Alveolar Proteinosis
- Chimera Disorder
- Chromosomal Translocation
- Leukemia, Myelocytic, Acute
- Nervousness
- Asthma
- Bipolar Disorder
- Leukemogenesis
Interacting Proteins
- CSF2
- IL5
- IL5RA
- ITGB1
- JAK2
Pathways
- Pathogenesis
- Immune Response
- Localization
- Protein Phosphorylation
- Initiation Of Signal Transduction
- Cell Proliferation
- Endocytosis
- Virulence
- Cell Death
- Eosinophil Differentiation
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CSF2RB
bosterbio.com/bosterbio-gene-info-cards/CSF2RB
References
PMID: 1702217 by Hayashida K., et al. Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): reconstitution of a high-affinity GM-CSF receptor.
PMID: 17828305 by Kao C.J., et al. CBAP interacts with the un-liganded common beta-subunit of the GM- CSF/IL-3/IL-5 receptor and induces apoptosis via mitochondrial dysfunction.