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- Table of Contents
Facts about Adapter molecule crk.
Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.
Human | |
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Gene Name: | CRK |
Uniprot: | P46108 |
Entrez: | 1398 |
Belongs to: |
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CRK family |
adapter molecule crk; avian sarcoma virus CT10 (v-crk) oncogene homolog; Crk; CRKII; p38; Proto-oncogene c-Crk; v-crk avian sarcoma virus CT10 oncogene homolog; v-crk sarcoma virus CT10 oncogene homolog (avian)
Mass (kDA):
33.831 kDA
Human | |
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Location: | 17p13.3 |
Sequence: | 17; NC_000017.11 (1420693..1456232, complement) |
Cytoplasm. Cell membrane. Translocated to the plasma membrane upon cell adhesion.
PMID: 1630456 by Matsuda M., et al. Two species of human CRK cDNA encode proteins with distinct biological activities.
PMID: 8378094 by Fioretos T., et al. CRK proto-oncogene maps to human chromosome band 17p13.