Crim1 Antibodies

AND Crim1 ELISA kits, Crim1 Proteins

Many biological assays use antibodies to detect Crim1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Crim1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Crim1 antibodies...

We validate the specificity of these antibodies to Crim1 by testing them on tissues known to express Crim1 positively and negatively. Browse below to find the Crim1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Crim1 Infographic by Boster Bio

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Anti-CRIM1 Antibody

1 Citations

Human

ELISA, IF, WB

$449
Cat # A06053
0.1 mg

Crim1 Overview

Facts about Cysteine-rich motor neuron 1 protein.

Cysteine-rich motor neuron 1 protein (Crim1)

May play a role in CNS development by interacting with growth factors implicated in motor neuron survival and differentiation. May play a role in capillary formation and maintenance during angiogenesis.

Modulates BMP activity by changing its processing and delivery to the cell surface (By similarity). .

Gene Information

Mouse
Gene Name:	Crim1
Uniprot:	Q9JLL0
Entrez:	50766

Family

Belongs to:

No superfamily

Alternative Names

CRIM1; CRIM-1; cysteine rich transmembrane BMP regulator 1 (chordin-like); cysteine-rich motor neuron 1 protein; cysteine-rich motor neuron 1; Cysteine-rich repeat-containing protein S52; MGC138194; S52

Molecular Weight

Mass (kDA):
114.066 kDA

Genomic Context


Mouse

Location:	17\|17 E2
Sequence:	17;

Tissue Specificity

Expressed during embryonic development in brain, kidney, spinal chord, testis, lens, vibrissae, pinna, tooth primordia and in specific regions of the CNS. Expressed in adult lens. Displays male-specific expression in the fetal gonads with the strongest expression in the Sertoli cells of developing testis.

Diseases

Malignant Neoplasms
Nervousness
Kidney Diseases
Fibrosis
Neoplasms
Congenital Abnormality
Tissue Adhesions
Syndactyly
Rubella
Malignant Tumor Of Eye
Complex Regional Pain Syndromes
Malignant Tumor Of Colon

Carcinoma
Carcinogenesis
Injury To Kidney
Cardiovascular Diseases
Hydronephrosis
Tumor Angiogenesis
Paraplegia

Pathways

Cell Adhesion
Gastrulation
Cell Growth
Secretion
Transport
Fibril Organization
Osteoblast Differentiation
Tube Formation
Pigmentation
Epiboly
System Development
Stem Cell Proliferation
Cell Differentiation

Collagen Fibril Organization
Central Nervous System Development
Cell-cell Adhesion
Cell Proliferation
Cell Development
Peristalsis
Mrna Transport

PTMs

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Crim1

References

PMID: 10642437 by Kolle G.V., et al. CRIM1, a novel gene encoding a cysteine-rich repeat protein, is developmentally regulated and implicated in vertebrate CNS development and organogenesis.

PMID: 11084657 by Georgas K., et al. Characterisation of Crim1 expression in the developing mouse urogenital tract reveals a sexually dimorphic gonadal expression pattern.

1 Publications of Boster Crim1 Antibodies & ELISA Kits

PubMed ID: 10.1016/j.expneurol.2019.112970, Roles of Reelin/Disabled1 pathway on functional recovery of hemiplegic mice afte...

*More publications can be found for each product on its corresponding product page