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- Table of Contents
Facts about Protein disulfide isomerase CRELD1.
Human | |
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Gene Name: | CRELD1 |
Uniprot: | Q96HD1 |
Entrez: | 78987 |
Belongs to: |
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CRELD family |
atrioventricular septal defect 2; AVSD2; CIRRIN; CRELD1; cysteine-rich with EGF-like domain protein 1; cysteine-rich with EGF-like domains 1; DKFZp566D213
Mass (kDA):
45.44 kDA
Human | |
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Location: | 3p25.3 |
Sequence: | 3; NC_000003.12 (9933788..9945406) |
Highly expressed in fetal lung, liver, kidney, adult heart, brain and skeletal muscle. Weakly expressed in placenta, fetal brain, and adult lung, liver, kidney and pancreas.
Membrane; Multi-pass membrane protein.
PMID: 12137942 by Rupp P.A., et al. Identification, genomic organization and mRNA expression of CRELD1, the founding member of a unique family of matricellular proteins.
PMID: 23027870 by Hansen H.G., et al. Hyperactivity of the Ero1alpha oxidase elicits endoplasmic reticulum stress but no broad antioxidant response.