Carboxypeptidase Z Antibodies

AND CPZ ELISA kits, Carboxypeptidase Z Proteins

Many biological assays use antibodies to detect Carboxypeptidase Z, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Carboxypeptidase Z in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Carboxypeptidase Z antibodies...

We validate the specificity of these antibodies to Carboxypeptidase Z by testing them on tissues known to express CPZ positively and negatively. Browse below to find the CPZ antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CPZ Infographic by Boster Bio

All CPZ Products

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Anti-Carboxypeptidase Z CPZ Antibody

Human, Rat

ELISA, WB

$380
Cat # A04337
100ul

Carboxypeptidase Z (CPZ) (NM_003652) Human Over-expression Lysate

Human

$960
Cat # LS008532
100 µg

CPZ Overview

Facts about Carboxypeptidase Z.

CPZ 3D structure. Source: alphafold

Carboxypeptidase Z (CPZ)

Cleaves substrates with C-terminal arginine residues. Probably modulates the Wnt signaling pathway, by cleaving some undefined protein.

May play a role in cleavage during prohormone processing. .

Gene Information

Human
Gene Name:	CPZ
Uniprot:	Q66K79
Entrez:	8532

Family

Belongs to:

peptidase M14 family

Alternative Names

Carboxypeptidase Z

Molecular Weight

Mass (kDA):
73.655 kDA

Genomic Context


Human

Location:	4p16.1
Sequence:	4; NC_000004.12 (8592660..8619761)

Tissue Specificity

In placenta, it is present within invasive trophoblasts and in the surrounding extracellular space. Also present in amnion cells, but is not readily apparent in the extracellular matrix of this cell type. Present in normal pituitary gland and neoplastic pituitary gland (especially POMC-, GH- and PRL-producing adenomas) (at protein level). Widely expressed.

Subcellular Localizations

Secreted, extracellular space, extracellular matrix.

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CPZ

References

PMID: 9099699 by Song L., et al. Cloning and expression of human carboxypeptidase Z, a novel metallocarboxypeptidase.

PMID: 10080937 by Novikova E.G., et al. Purification and characterization of human metallocarboxypeptidase Z.