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- Table of Contents
Facts about Carboxypeptidase D.
Human | |
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Gene Name: | CPD |
Uniprot: | O75976 |
Entrez: | 1362 |
Belongs to: |
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peptidase M14 family |
carboxypeptidase D; GP180; metallocarboxypeptidase D
Mass (kDA):
152.931 kDA
Human | |
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Location: | 17q11.2 |
Sequence: | 17; NC_000017.11 (30378927..30469989) |
Highly expressed in placenta, pancreas and hepatoma cells. Lower levels found in skeletal muscle, heart and colon carcinoma and melanoma cell lines.
Cell membrane; Single-pass type I membrane protein.
PMID: 9714835 by Ishikawa T., et al. Cloning, functional expression, and chromosomal localization of the human and mouse gp180-carboxypeptidase D-like enzyme.
PMID: 9355738 by Tan F., et al. Sequence of human carboxypeptidase D reveals it to be a member of the regulatory carboxypeptidase family with three tandem active site domains.