COQ7 Antibodies

AND COQ7 ELISA kits, COQ7 Proteins

Many biological assays use antibodies to detect COQ7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with COQ7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop COQ7 antibodies...

We validate the specificity of these antibodies to COQ7 by testing them on tissues known to express COQ7 positively and negatively. Browse below to find the COQ7 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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COQ7 Infographic by Boster Bio

All COQ7 Products

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Specificity

Applications

Price

Anti-COQ7 Antibody

Human, Mouse, Rat

$405
Cat # A04682
100ul

COQ7 (NM_016138) Human Recombinant Protein

$813
Cat # PROTQ99807
20 µg

COQ7 Overview

Facts about 5-demethoxyubiquinone hydroxylase, mitochondrial.

COQ7 3D structure. Source: alphafold

5-demethoxyubiquinone hydroxylase, mitochondrial (COQ7)

Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) through ubiquinone biosynthesis. Has also a structural function in the COQ enzyme complex, stabilizing other COQ polypeptides.

Involved in lifespan determination in a ubiquinone-independent manner. .

Gene Information

Human
Gene Name:	COQ7
Uniprot:	Q99807
Entrez:	10229

Family

Belongs to:

COQ7 family

Alternative Names

CAT5; CLK1; CLK-1; Coenzyme Q biosynthesis protein 7 homolog; coenzyme Q, 7 (rat, yeast) homolog; coenzyme Q7 homolog, ubiquinone (yeast); COQ7 coenzyme Q, 7 homolog ubiquinone; placental protein KG-20; Timing protein clk-1 homolog; ubiquinone biosynthesis protein COQ7 homolog

Molecular Weight

Mass (kDA):
24.277 kDA

Genomic Context


Human

Location:	16p12.3
Sequence:	16; NC_000016.10 (19067595..19080095)

Tissue Specificity

Expressed dominantly in heart and skeletal muscle.

Subcellular Localizations

Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.

Diseases

Hypokinesia
Malignant Neoplasms
Trematode Infections
Dyslipidemias
Reperfusion Injury
Brain Ischemia
Neurodegenerative Disorders
Mitochondrial Diseases
Down Syndrome
Trauma, Nervous System
Teratogenic Effect
Heart Block

Left Ventricular Hypertrophy
Congenital Heart Defects
Hermaphroditism
Cerebrovascular Accident
Nervousness
Exposure To Mercury (event)
Hyperlipidemia

Interacting Proteins

COQ3
COQ4
COQ5
COQ6
COQ9

Pathways

Aging
Transport
Electron Transport
Electron Transport Chain
Neurogenesis
Hypersensitivity
Localization
Intracellular Transport
Rhythmic Behavior
Cell Proliferation
Tricarboxylic Acid Cycle
Immune Response
Gluconeogenesis

Oxidative Phosphorylation
Cardiac Conduction
Response To Oxidative Stress
Cellular Respiration
Release Of Cytochrome C From Mitochondria
Respiratory Electron Transport Chain
Cell Death

PTMs

Hydroxylation
Phosphorylation

Carboxylation
Oxidation

Research Areas

Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/COQ7

References

PMID: 10373327 by Asaumi S., et al. Orthologues of the Caenorhabditis elegans longevity gene clk-1 in mouse and human.

PMID: 10501970 by Vajo Z., et al. Conservation of the Caenorhabditis elegans timing gene clk-1 from yeast to human: a gene required for ubiquinone biosynthesis with potential implications for aging.