Coatomer subunit gamma-1 Antibodies

AND COPG1 ELISA kits, Coatomer subunit gamma-1 Proteins

Many biological assays use antibodies to detect Coatomer subunit gamma-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Coatomer subunit gamma-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Coatomer subunit gamma-1 antibodies...

We validate the specificity of these antibodies to Coatomer subunit gamma-1 by testing them on tissues known to express COPG1 positively and negatively. Browse below to find the COPG1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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COPG1 Infographic by Boster Bio

All COPG1 Products

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Anti-Coatomer subunit gamma-1 COPG1 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A10394
100ul

COPG (COPG1) (NM_016128) Human Recombinant Protein

$1062
Cat # PROTQ9Y678
20 µg

COPG (COPG1) (NM_016128) Human Over-expression Lysate

Human

$628
Cat # LS022820
100 µg

COPG1 Overview

Facts about Coatomer subunit gamma-1.

COPG1 3D structure. Source: alphafold

Coatomer subunit gamma-1 (COPG1)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transportation of dilysine-tagged proteins.

In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are little GTP-binding proteins; the complex also influences the Golgi structural integrity, in addition to the processing, activity, and endocytic recycling of LDL receptors. Required for restricting lipid storage in lipid droplets.

Gene Information

Human
Gene Name:	COPG1
Uniprot:	Q9Y678
Entrez:	22820

Family

Belongs to:

COPG family

Alternative Names

coat protein gamma-cop; coatomer protein complex, subunit gamma 1; coatomer protein complex, subunit gamma; COPG1coatomer subunit gamma; FLJ21068; Gamma-coat protein; gamma-COP

Molecular Weight

Mass (kDA):
97.718 kDA

Genomic Context


Human

Location:	3q21.3
Sequence:	3; NC_000003.12 (129249575..129277773)

Subcellular Localizations

Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. Predominantly located in the cis-Golgi apparatus.

Interacting Proteins

GBF1
NUDCD1
SACM1L

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/COPG1

References

PMID: 11056392 by Futatsumori M., et al. Identification and characterization of novel isoforms of COP I subunits.

PMID: 20674546 by Wang Y.N., et al. COPI-mediated retrograde trafficking from the Golgi to the ER regulates EGFR nuclear transport.