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- Table of Contents
Facts about Collagen alpha-1(VI) chain.
Human | |
---|---|
Gene Name: | COL6A1 |
Uniprot: | P12109 |
Entrez: | 1291 |
Belongs to: |
---|
type VI collagen family |
Collagen 6; collagen alpha-1(VI) chain; collagen VI, alpha-1 polypeptide; collagen, type VI, alpha 1; Collagen-6; human mRNA for collagen VI alpha-1 C-terminal globular domain10alpha 1 (VI) chain (61 AA); OPLL
Mass (kDA):
108.529 kDA
Human | |
---|---|
Location: | 21q22.3 |
Sequence: | 21; NC_000021.9 (45981770..46005048) |
Secreted, extracellular space, extracellular matrix.
If you are looking for a high-affinity antibody to detect COL6A1 protein, you've come to the right place. Boster offers high-affinity primary antibodies that are well-cited over the last 25 years and are trusted by researchers worldwide. Boster antibodies have been validated in Western Blotting, Immunohistochemistry, and ELISA.
High-affinity primary antibodies are immunoglobulins that specifically bind to a target protein. They are commonly measured by the amount of binding to the targeted antigen and are often rated by their specificity and affinity. A good primary antibody will detect, purify, and measure the target protein. Boster Bio's products are tested to be highly specific against COL6A1 in human and mouse.
The Boster Bio Tissue or Cell Total Protein Extraction Kit provides everything necessary to perform protein extraction from tissue or cells. It breaks the cell membrane and separates the cytoplasmic and nuclear fractions. This kit also allows for the collection of nucleoli and the desalted soluble cytoplasmic fractions, which can be used for pull-down assays and protein interactions. Using this kit, researchers can achieve the purest extract possible, while also ensuring a high yield and fast turnaround for rapid studies.
The Boster Cytoplasmic and Nuclear Protein Extraction Kit is an excellent choice for scientists seeking to extract nuclear protein from fresh tissues and cultured cells. The Boster Cytoplasmic and Nuclear Protein Extraction Kit is stable at 4degC for one year. The kits also feature buffer that has been dialyzed for maximum potency. Boster's Cytoplasmic and Nuclear Protein Extraction Kit provides a complete set of reagents to separate nuclear and cytoplasmic proteins from cells.
Boster produces a wide variety of antibodies for various applications. All of its antibodies have been validated against known positive and negative samples, ensuring high specificity and high affinity. Moreover, Boster rewards the first reviewers of their products with product credits. These incentives are extended to scientists worldwide and are not limited to the United States. You can use Boster antibodies to test new discoveries. It is also recommended that you use Boster's anti-mouse serum.
The Cayman's Protein Determination (BCA) Kit is a highly sensitive and accurate ELISA kit. It can be used for the quantitative determination of proteins from water, serum, urine, and plasma. The BCA Protein Quantitative Kit can be used for studies in the field of biomedicine, biotechnology, and clinical research. The BCA Colorimetric Protein Assay uses a proprietary platform to deliver high-sensitivity ELISA kits.
The BCA Protein Assay is a highly sensitive, two-component enzyme that combines a biuret reaction with a sensitive colorimetric detection of cuproate ions. The enzyme is activated by proteins containing at least three amino acid residues. Peptides that contain three or more amino acid residues form a colored chelate complex with the cupric ions in an alkaline environment. Sodium potassium tartrate is necessary to perform the reaction.
PMID: 2551668 by Chu M.-L., et al. Sequence analysis of alpha 1(VI) and alpha 2(VI) chains of human type VI collagen reveals internal triplication of globular domains similar to the A domains of von Willebrand factor and two alpha 2(VI) chain variants that differ in the carboxy terminus.
PMID: 8168508 by Tillet E., et al. Recombinant expression and structural and binding properties of alpha 1(VI) and alpha 2(VI) chains of human collagen type VI.