COL4A6 Antibodies

AND COL4A6 ELISA kits, COL4A6 Proteins

Many biological assays use antibodies to detect COL4A6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with COL4A6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop COL4A6 antibodies...

We validate the specificity of these antibodies to COL4A6 by testing them on tissues known to express COL4A6 positively and negatively. Browse below to find the COL4A6 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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COL4A6 Infographic by Boster Bio

All COL4A6 Products

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Product

Figures

Specificity

Applications

Price

Anti-COL4A6 (G1223) Antibody

Human

IHC

$405
Cat # A06082
100ul

Anti-Collagen alpha-6(IV) chain COL4A6 Antibody

Human

ELISA, IF, IHC, WB

$380
Cat # A06082-1
100ul

COL4A6 Overview

Facts about Collagen alpha-6(IV) chain.

COL4A6 3D structure. Source: alphafold

Collagen alpha-6(IV) chain (COL4A6)

Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. .

Gene Information

Human
Gene Name:	COL4A6
Uniprot:	Q14031
Entrez:	1288

Family

Belongs to:

type IV collagen family

Alternative Names

collagen alpha 6 type IV; collagen alpha-6(IV) chain; collagen IV, alpha-6 polypeptide; collagen of basement membrane, alpha-6; collagen, type IV, alpha 6; CXDELq22.3; DELXq22.3; dJ889N15.4 (Collagen Alpha 6(IV)); EC 2.7.7.8; MGC88184

Molecular Weight

Mass (kDA):
163.807 kDA

Genomic Context


Human

Location:	Xq22.3
Sequence:	X; NC_000023.11 (108155607..108439493, complement)

Subcellular Localizations

Secreted, extracellular space, extracellular matrix, basement membrane.

Diseases

Hereditary Nephritis
Leiomyomatosis
Neoplasms
Alport Syndrome, X-linked
Kidney Diseases
Kidney Failure
Esophageal Neoplasms
Nephritis
Uterine Fibroids
Complete Hearing Loss
Kidney Failure, Chronic
Glioblastoma

Hereditary Diseases
Alport Syndrome With Diffuse Leiomyomatosis
Sensorineural Hearing Loss (disorder)
Kidney Neoplasm
Constipation
Benign Neoplasm

Pathways

Cell Proliferation
Localization
Pathogenesis
Methylation
Smooth Muscle Cell Proliferation
Muscle Cell Proliferation
Translation
Osteoblast Differentiation

Bone Remodeling
Wound Healing

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/COL4A6

References

PMID: 8125972 by Oohashi T., et al. Identification of a new collagen IV chain, alpha 6(IV), by cDNA isolation and assignment of the gene to chromosome Xq22, which is the same locus for COL4A5.

PMID: 8175748 by Zhou J., et al. Complete primary structure of the sixth chain of human basement membrane collagen, alpha 6(IV). Isolation of the cDNAs for alpha 6(IV) and comparison with five other type IV collagen chains.