COL4A5 Antibodies

AND COL4A5 ELISA kits, COL4A5 Proteins

Many biological assays use antibodies to detect COL4A5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with COL4A5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop COL4A5 antibodies...

We validate the specificity of these antibodies to COL4A5 by testing them on tissues known to express COL4A5 positively and negatively. Browse below to find the COL4A5 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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COL4A5 Infographic by Boster Bio

All COL4A5 Products

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Specificity

Applications

Price

Anti-Collagen alpha-5(IV) chain COL4A5 Antibody

Human

$405
Cat # A01457
100ul

Anti-Collagen alpha-5(IV) chain COL4A5 Antibody

Human, Mouse

ELISA, IF, IHC

$380
Cat # A01457-1
100ul

COL4A5 Overview

Facts about Collagen alpha-5(IV) chain.

COL4A5 3D structure. Source: alphafold

Collagen alpha-5(IV) chain (COL4A5)

Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. .

Gene Information

Human
Gene Name:	COL4A5
Uniprot:	P29400
Entrez:	1287

Family

Belongs to:

type IV collagen family

Alternative Names

Collagen alpha-5(IV) chain

Molecular Weight

Mass (kDA):
161.044 kDA

Genomic Context


Human

Location:	Xq22.3
Sequence:	X; NC_000023.11 (108439838..108697545)

Tissue Specificity

Isoform 2 is found in kidney.

Subcellular Localizations

Secreted, extracellular space, extracellular matrix, basement membrane.

Diseases

Alport syndrome 1, X-linked (ATS1)

PTMs

Disulfide bond

Glycoprotein

Hydroxylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/COL4A5

References

PMID: 8120014 by Zhou J., et al. Structure of the human type IV collagen COL4A5 gene.

PMID: 1352287 by Zhou J., et al. Complete amino acid sequence of the human alpha 5 (IV) collagen chain and identification of a single-base mutation in exon 23 converting glycine 521 in the collagenous domain to cysteine in an Alport syndrome patient.